CAS 147149-84-6

4-Bromo-5-methylisatin

Description:

4-Bromo-5-methylisatin is an organic compound characterized by its unique structure, which includes a bromine atom and a methyl group attached to an isatin core. Isatin itself is a bicyclic compound derived from indole, featuring a carbonyl group and an amine. The presence of the bromine substituent at the 4-position and the methyl group at the 5-position contributes to its chemical reactivity and potential biological activity. This compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. It is of interest in medicinal chemistry due to its potential applications in drug development, particularly in the synthesis of various bioactive molecules. The compound may also display interesting properties such as fluorescence or specific interactions with biological targets, making it a subject of research in fields like pharmacology and material science. As with many halogenated compounds, safety precautions should be taken when handling 4-Bromo-5-methylisatin due to potential toxicity and environmental impact.

Formula: C₉H₆BrNO₂

InChI: InChI=1/C9H6BrNO2/c1-4-2-3-5-6(7(4)10)8(12)9(13)11-5/h2-3H,1H3,(H,11,12,13)

SMILES: Cc1ccc2c(c1Br)C(=O)C(=O)N2

Synonyms:

• 1H-indole-2,3-dione, 4-bromo-5-methyl-
• 4-bromo-5-methyl-1H-indole-2,3-dione
• 4-Bromo-5-Methyl-2,3-Indolinedione

1H-Indole-2,3-dione, 4-bromo-5-methyl-

CAS: 147149-84-6

Formula: C₉H₆BrNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 240.0534

Ref: IN-DA001EO8

4-Bromo-5-methylindoline-2,3-dione

CAS: 147149-84-6

Formula: C₉H₆BrNO₂

Purity: 95%

Color and Shape: Solid, Orange crystalline powder

Molecular weight: 240.056

Ref: 10-F222776

4-Bromo-5-methyl-1H-indole-2,3-dione

CAS: 147149-84-6

4-Bromo-5-methyl-1H-indole-2,3-dione is a synthetic molecule that has been shown to have neuroprotective effects. It inhibits the production of proinflammatory cytokines, such as tnf-α and il-6, by binding to survivin. 4Bromo-5 methyl 1Hindole 2,3 dione also binds to the viral capsid protein and blocks virus infection. This compound has been shown to inhibit viral replication in vitro as well as provide protection against alphavirus infection in mice.

Formula: C₉H₆BrNO₂

Purity: Min. 95%

Molecular weight: 240.05 g/mol

Ref: 3D-FB19157

4-Bromo-5-methyl-1H-indole-2,3-dione

Controlled Product

CAS: 147149-84-6

Applications Reagent used in the production of Nolatrexed Dihydrochloride.
References Polychronopoulos, P., et al.: J. Med. Chem., 47, 935 (2004), Sirisoma, N., et al.: Bioorg. Med. Chem. Lett., 19, 2710 (2009),

Formula: C₉H₆BrNO₂

Color and Shape: Neat

Molecular weight: 240.05

Ref: TR-B685380

4-Bromo-5-methylisatin

CAS: 147149-84-6

4-Bromo-5-methylisatin

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 240.05g/mol

Ref: 54-OR7044