CAS 147221-93-0
:Delavirdine mesylate
Description:
Delavirdine mesylate is a non-nucleoside reverse transcriptase inhibitor (NNRTI) primarily used in the treatment of HIV infection. It functions by binding to the reverse transcriptase enzyme, thereby inhibiting the replication of the virus. This compound is characterized by its chemical structure, which includes a pyridine ring and a substituted phenyl group, contributing to its pharmacological activity. Delavirdine mesylate is typically administered orally and is known for its relatively short half-life, necessitating multiple daily doses for effective viral suppression. It exhibits a moderate bioavailability and is metabolized primarily by the liver, with interactions noted with various cytochrome P450 enzymes. Common side effects may include rash, gastrointestinal disturbances, and potential liver enzyme elevations. Due to its specific mechanism of action, it is often used in combination with other antiretroviral agents to enhance therapeutic efficacy and reduce the risk of resistance development. Overall, Delavirdine mesylate plays a significant role in the management of HIV, contributing to improved patient outcomes when used appropriately.
Formula:C23H32N6O6S2
InChI:InChI=1/C22H28N6O3S.CH4O3S/c1-15(2)24-19-5-4-8-23-21(19)27-9-11-28(12-10-27)22(29)20-14-16-13-17(26-32(3,30)31)6-7-18(16)25-20;1-5(2,3)4/h4-8,13-15,24-26H,9-12H2,1-3H3;1H3,(H,2,3,4)
InChI key:InChIKey=MEPNHSOMXMALDZ-UHFFFAOYSA-N
SMILES:N(C(C)C)C1=C(N=CC=C1)N2CCN(C(=O)C3=CC=4C(N3)=CC=C(NS(C)(=O)=O)C4)CC2.S(C)(=O)(=O)O
Synonyms:- Delavirdine methane sulfonate
- Methanesulfonamide, N-[2-[[4-[3-[(1-methylethyl)amino]-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]-, methanesulfonate (1:1)
- N-[2-({4-[3-(propan-2-ylamino)pyridin-2-yl]piperazin-1-yl}carbonyl)-1H-indol-5-yl]methanesulfonamide methanesulfonate (1:1)
- Piperazine, 1-[3-[(1-methylethyl)amino]-2-pyridinyl]-4-[[5-[(methylsulfonyl)amino]-1H-indol-2-yl]carbonyl]-, monomethanesulfonate
- Rescripta
- Rescriptor
- U 90152E
- U 90152S
- U 90152T
- Delavirdine mesylate
- N-[2-[[4-[3-[(1-Methylethyl)amino]-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide mesylate
- MethanesulfonaMide, N-[2-[[4-[3-[(1-Methylethyl)aMino]-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]-, Methanesulfonate
- C08087
- N-[2-[[4-[3-[(1-Methylethyl)aMino]-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]MethanesulfonaMide Methanesulfonate
- See more synonyms
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Found 7 products.
Methanesulfonamide, N-[2-[[4-[3-[(1-methylethyl)amino]-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]-, methanesulfonate (1:1)
CAS:Formula:C23H32N6O6S2Purity:%Color and Shape:SolidMolecular weight:552.6668N-(2-(4-(3-(Isopropylamino)Pyridin-2-yl)Piperazine-1-Carbonyl)-1H-Indol-5-yl)Methanesulfonamide Methanesulfonate
CAS:N-(2-(4-(3-(Isopropylamino)Pyridin-2-yl)Piperazine-1-Carbonyl)-1H-Indol-5-yl)Methanesulfonamide MethanesulfonatePurity:99%Molecular weight:552.67g/molDelavirdine mesylate
CAS:<p>Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).</p>Formula:C23H32N6O6S2Purity:99.99%Color and Shape:Light Brown SolidMolecular weight:552.67Delavirdine Mesylate
CAS:Controlled Product<p>Applications A bisheteroarylpiperazine (BHAP) reverse transcriptase inhibitor.<br>References Dueweke, T.J., et al.: Antimicrob. Ag. Chemother., 37, 1127 (1993), Althaus, I.W., et al.: Biochem. Pharmacol., 47, 2017 (1994)<br></p>Formula:C22H28N6O3S·CH4O3SColor and Shape:NeatMolecular weight:552.67Delavirdine mesylate
CAS:<p>Non-nucleoside reverse transcriptase inhibitor; antiviral agent against HIV</p>Formula:C23H32N6O6S2Purity:Min. 95%Color and Shape:White To Yellow SolidMolecular weight:552.18248
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