CAS 147254-64-6: Ranirestat

Description: Ranirestat is a chemical compound primarily studied for its potential therapeutic applications, particularly in the treatment of diabetic complications. It functions as an aldose reductase inhibitor, which means it inhibits the enzyme responsible for converting glucose into sorbitol, thereby potentially reducing the accumulation of sorbitol in tissues and mitigating osmotic and oxidative stress associated with diabetes. The molecular structure of Ranirestat includes specific functional groups that contribute to its biological activity and solubility properties. It is typically administered in a pharmaceutical formulation, and its efficacy and safety profile have been evaluated in various clinical studies. As with many pharmacological agents, the characteristics of Ranirestat, including its pharmacokinetics, metabolism, and potential side effects, are crucial for understanding its role in medical applications. Overall, Ranirestat represents a significant area of research in the context of managing diabetic complications and improving patient outcomes.

Formula: C₁₇H₁₁BrFN₃O₄

InChI: InChI=1S/C17H11BrFN3O4/c18-10-4-3-9(11(19)6-10)8-21-14(24)12-2-1-5-22(12)17(16(21)26)7-13(23)20-15(17)25/h1-6H,7-8H2,(H,20,23,25)/t17-/m1/s1

InChI key: InChIKey=QCVNMNYRNIMDKV-QGZVFWFLSA-N

SMILES: O=C1C2=CC=CN2C3(C(=O)NC(=O)C3)C(=O)N1CC4=CC=C(Br)C=C4F

Synonyms:

• (3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone
• (3R)-2′-(4-Bromo-2-fluorobenzyl)-1′,2′,3′,4′-tetrahydrospiro[pyrrolidine-3,4′-pyrrolo[1,2-a]pyrazine]-1′,2,3′,5-tetraone
• (3R)-2′-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4′-1′H-pyrrolo[1,2-a]pyrazine]-1′,2,3′,5(2′H)-tetraone
• (3R)-2′-[(4-Bromo-2-fluorophenyl)methyl]spiro[pyrrolidine-3,4′(1′H)-pyrrolo[1,2-a]pyrazine]-1′,2,3′,5(2′H)-tetrone
• As-3201
• Ranirestat
• SX-3030(racemate)
• SX-3202((+)-(S)-isomer)
• Spiro[pyrrolidine-3,4′(1′H)-pyrrolo[1,2-a]pyrazine]-1′,2,3′,5(2′H)-tetrone, 2′-[(4-bromo-2-fluorophenyl)methyl]-, (-)-
• Spiro[pyrrolidine-3,4′(1′H)-pyrrolo[1,2-a]pyrazine]-1′,2,3′,5(2′H)-tetrone, 2′-[(4-bromo-2-fluorophenyl)methyl]-, (3R)-
• Sx-3201

Ranirestat

CAS: 147254-64-6

• Purity: 96.09%
• Molecular weight: 420.19g/mol

Ranirestat

CAS: 147254-64-6

• Formula: C₁₇H₁₁BrFN₃O₄
• Color and Shape: Neat
• Molecular weight: 420.189

Ranirestat

CAS: 147254-64-6

Ranirestat (AS-3201) is an AR inhibitor with neuroprotective properties that improves peripheral nerve dysfunction in …

• Formula: C₁₇H₁₁BrFN₃O₄
• Purity: 96.10% - 99.44%
• Color and Shape: Solid
• Molecular weight: 420.19

Ranirestat

CAS: 147254-64-6

Ranirestat is a fatty acid that is used as a pharmaceutical agent. It is known …

• Formula: C₁₇H₁₁BrFN₃O₄
• Purity: Min. 95%
• Molecular weight: 420.19 g/mol