CAS 147359-76-0

2H-Benzimidazol-2-one,1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-,hydrochloride (1:1)

Description:

2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-, hydrochloride (1:1), with CAS number 147359-76-0, is a chemical compound characterized by its complex structure, which includes a benzimidazole core and a piperazine moiety. This compound typically exhibits properties associated with both heterocyclic and aromatic compounds, contributing to its potential biological activity. The presence of the trifluoromethyl group enhances lipophilicity and may influence the compound's pharmacokinetic properties. As a hydrochloride salt, it is likely to be more soluble in water compared to its free base form, which is advantageous for formulation in pharmaceutical applications. The compound may exhibit various biological activities, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. Its specific interactions, mechanisms of action, and potential applications would require further investigation through experimental studies. Safety and handling considerations should also be taken into account due to the presence of fluorinated groups, which can pose environmental and health risks.

Formula: C₂₀H₂₁F₃N₄O·HCl

Synonyms:

• 2H-Benzimidazol-2-one,1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-,monohydrochloride
• Flibanserin hydrochloride
• 2H-Benzimidazol-2-one,1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-,hydrochloride (1:1)
• Flibanserin iMpurity
• Flibanserin HCl
• Flibanserin Hydrochloride USP/EP/BP

2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-, hydrochloride (1:1)

CAS: 147359-76-0

Formula: C₂₀H₂₂ClF₃N₄O

Purity: 95%

Color and Shape: Solid

Molecular weight: 426.8631

Ref: IN-DA001EU9

1-(2-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one hydrochloride

CAS: 147359-76-0

1-(2-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one hydrochloride

Purity: 95%

Molecular weight: 426.87g/mol

Ref: 54-PC1007684

Flibanserin HCl

CAS: 147359-76-0

Formula: C₂₀H₂₁F₃N₄O·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 390.41 36.46

Ref: 4Z-F-451

Flibanserin hydrochloride

CAS: 147359-76-0

Flibanserin HCl: oral 5-HT1A agonist & 5-HT2A antagonist, Ki values 1 nM & 49 nM, for HSDD, has antidepressant/anxiolytic properties.

Formula: C₂₀H₂₂ClF₃N₄O

Color and Shape: Solid

Molecular weight: 426.87

Ref: TM-T62324

Flibanserin Hydrochloride

Controlled Product

CAS: 147359-76-0

Applications Flibanserin is a 5-HT1A agonist and 5-HT2A antagonist that is developed for the treatment of hypoactive sexual desire disorder in women (1,2).
References 1) Gelez, H., et. al.: (2013) Psychopharmacology 230 :639-52.2) Katz, M., et. al.: (2013) J. Sex. Med. 10, 1807-15

Formula: C₂₀H₂₁F₃N₄O·ClH

Color and Shape: Neat

Molecular weight: 426.86

Ref: TR-F401270

Flibanserin Hydrochloride

CAS: 147359-76-0

Formula: C₂₀H₂₁F₃N₄OHCl

Molecular weight: 390.41 : 36.46

Ref: ST-EA-CP-F93003