CAS 147366-41-4

1-Ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]pyridinium chloride (1:1)

Description:

1-Ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]pyridinium chloride (1:1), with CAS number 147366-41-4, is a complex organic compound characterized by its unique structural features, which include a pyridinium ring and thiazolidine moieties. This substance exhibits properties typical of quaternary ammonium compounds, such as solubility in polar solvents and potential antimicrobial activity. The presence of the benzothiazole group suggests possible applications in pharmaceuticals or as a dye, given its conjugated system that may exhibit fluorescence. The compound's chloride salt form indicates it is likely to be stable and soluble in aqueous environments. Its intricate structure may also contribute to specific biological activities, making it of interest in medicinal chemistry. However, detailed studies on its toxicity, stability, and reactivity would be necessary to fully understand its potential applications and safety profile. As with many synthetic organic compounds, proper handling and storage conditions should be observed to ensure safety and integrity.

Formula: C₂₁H₂₂ClN₃OS₂

InChI: InChI=1/C21H22N3OS2.ClH/c1-4-23-13-9-8-10-15(23)14-18-24(5-2)20(25)19(27-18)21-22(3)16-11-6-7-12-17(16)26-21;/h6-14H,4-5H2,1-3H3;1H/q+1;/p-1/b21-19+;

InChI key: InChIKey=VSKYOTRJSLYFHX-UHFFFAOYSA-M

SMILES: O=C1C(SC(=CC=2[N+](CC)=CC=CC2)N1CC)=C3N(C)C=4C(S3)=CC=CC4.[Cl-]

Synonyms:

• 1-Ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]pyridinium chloride (1:1)
• 1-ethyl-2-{(Z)-[(5E)-3-ethyl-5-(3-methyl-1,3-benzothiazol-2(3H)-ylidene)-4-oxo-1,3-thiazolidin-2-ylidene]methyl}pyridinium chloride
• FJ-776(formerly)
• Fj 776
• Mkt-077
• Pyridinium, 1-ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-, chloride
• Pyridinium, 1-ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-, chloride (1:1)
• Sdz-Mkt-077
• 1-Ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-pyridinium chloride
• MKT077;MKT-077;FJ-776
• MKT-077 >=98% (HPLC), powder

Pyridinium, 1-ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-, chloride (1:1)

CAS: 147366-41-4

Formula: C₂₁H₂₂ClN₃OS₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 432.0019

Ref: IN-DA001EV0

1-Ethyl-2-((Z)-((Z)-3-Ethyl-5-(3-mEthylbenzo[d]Thiazol-2(3H)-Ylidene)-4-oxoThiazolidin-2-Ylidene)mEthyl)Pyridin-1-Ium Chloride

CAS: 147366-41-4

1-Ethyl-2-((Z)-((Z)-3-Ethyl-5-(3-mEthylbenzo[d]Thiazol-2(3H)-Ylidene)-4-oxoThiazolidin-2-Ylidene)mEthyl)Pyridin-1-Ium Chloride

Purity: 95%

Molecular weight: 432.00g/mol

Ref: 54-OR1009464

MKT-077

CAS: 147366-41-4

MKT-077

Purity: ≥98%

Molecular weight: 432g/mol

Ref: 54-BUP04189

MKT-077

CAS: 147366-41-4

Formula: C₂₁H₂₂N₃OS₂Cl

Purity: (HPLC) ≥ 98.0%

Color and Shape: Orange-red crystalline powder or solid

Molecular weight: 432.00

Ref: 7W-GK8369

MKT-077

CAS: 147366-41-4

MKT-077 (FJ-776) is a cationic rhodacyanine dye that demonstrates antiproliferative activity against cancer cell lines.

Formula: C₂₁H₂₂ClN₃OS₂

Purity: 98.2%

Color and Shape: Solid

Molecular weight: 432

Ref: TM-T5152

1-Ethyl-2-((Z)-((Z)-3-ethyl-5-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-oxothiazolidin-2-ylidene)methyl)pyridin-1-ium chloride

CAS: 147366-41-4

Purity: 95.0%

Molecular weight: 432.0

Ref: 10-F544604

MKT-077

Controlled Product

CAS: 147366-41-4

Applications MKT-077 is used in the treatment of Alzheimer’s diseases and other tauopathie’s. Also, is a rhodacyanine derivative that selectively targets cancer cells and overcomes tamoxifen resistance
References Jinwal, U. K., et al.: Pharm. Nanotechnol., 2, 217, (2014); Koren, J., et al. : PLoS One, 7, 35566 (2012)

Formula: C₂₁H₂₂N₃OS₂·Ci

Color and Shape: Neat

Molecular weight: 432.0

Ref: TR-M425135

MKT-077

CAS: 147366-41-4

MKT-077 is a rhodacyanine dye analogue, which is a compound derived from the class of compounds known as rhodacyanines. This particular analogue is synthesized for its biochemical properties, specifically targeting mitochondrial functions. The mode of action of MKT-077 involves the selective accumulation within the mitochondria of cancer cells, where it induces mitochondrial stress and disrupts mitochondrial membrane potential. This disruption leads to apoptotic cell death, making it a potential agent in cancer treatment research.

Formula: C₂₁H₂₂ClN₃OS₂

Purity: Min. 95%

Molecular weight: 432 g/mol

Ref: 3D-XFA36641