CAS 1474-53-9

estriol 3-methyl ether

Description:

Estriol 3-methyl ether, with the CAS number 1474-53-9, is a synthetic derivative of estriol, a naturally occurring estrogen. This compound is characterized by its structural modifications that enhance its biological activity and stability. Estriol itself is a steroid hormone, and the methyl ether modification typically influences its solubility and receptor binding properties. The substance is often studied for its potential applications in hormone replacement therapy and its effects on various physiological processes. Estriol 3-methyl ether may exhibit estrogenic activity, which can impact reproductive health and other systems influenced by estrogen. Its chemical properties include a specific molecular weight and a defined melting point, which are crucial for its characterization and application in research. Additionally, safety and handling considerations are essential, as with all chemical substances, to mitigate any potential risks associated with exposure. Overall, estriol 3-methyl ether represents an important compound in the field of medicinal chemistry and endocrinology.

Formula: C₁₉H₂₆O₃

InChI: InChI=1/C19H26O3/c1-19-8-7-14-13-6-4-12(22-2)9-11(13)3-5-15(14)16(19)10-17(20)18(19)21/h4,6,9,14-18,20-21H,3,5,7-8,10H2,1-2H3/t14?,15?,16?,17-,18?,19?/m1/s1

InChI key: InChIKey=UHQGCIIQUZBJAE-QKDSSNGWSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(OC)=CC4)(CC1)[H])[H])(C[C@@H](O)[C@@H]2O)[H]

Synonyms:

• (16Alpha)-3-Methoxyestra-1,3,5(10)-Triene-16,17-Diol
• (16Alpha,17Beta)-3-Methoxyestra-1,3,5(10)-Triene-16,17-Diol
• (16α,17β)-3-Methoxyestra-1,3,5(10)-triene-16,17-diol
• 13β-Methyl-3-methoxygona-1,3,5(10)triene-16α,17β-diol
• 16α,17β-Estriol-3-methyl ether
• 3-Methoxyestriol
• E 2710
• Estra-1,3,5(10)-triene-16,17-diol, 3-methoxy-, (16α,17β)-
• Estra-1,3,5(10)-triene-16-alpha,17-beta-diol, 3-methoxy-
• Estra-1,3,5(10)-triene-16α,17β-diol, 3-methoxy-
• Estriol methyl ether
• Estriol-3-methyl ether
• Estriol 3-methyl ether
• 3-Methoxyestra-1,3,5(10)-triene-16a
• 3-Methoxy-1,3,5(10)-estratriene-16α,17β-diol
• (8R,9S,13S,14S,17S)-3-METHOXY-13-METHYL-7,8,9,11,12,13,14,15,16,17-DECAHYDRO-6H-CYCLOPENTA[A]PHENANTHREN-17-OL
• Conjugated Estrogens EP Impurity C
• 1,3,5(10)-estratriene-3,16α,17β-triol 3-methyl ether
• 3-Methoxyestra-1(10),2,4-triene-16α,17β-diol
• 3-METHYLESTRIOL
• 1,3,5(10)-ESTRATRIENE-3,17BETA-DIOL 3-METHYL ETHER
• 1,3,5(10)-Estratriene-3,16α,17β-triol 3-methyl ether, 3,16α,17β-Trihydroxy-1,3,5(10)-estratriene 3-methyl ether
• 3,16ALPHA,17BETA-TRIHYDROXY-1,3,5(10)-ESTRATRIENE 3-METHYL ETHER
• BETA-ESTRIOL 3-METHYL ETHER
• 1,3,5(10)-ESTRATRIEN-3,17-BETA-DIOL 3-METHYL ETHER
• BETA-ETHYLESTRADIOL 3-METHYL ETHER
• Estriol Impurity 3 (Estriol EP Impurity C)
• 3,16α,17β-Trihydroxy-1,3,5(10)-estratriene 3-methyl ether
• 5(10)-triene-16,17-diol,3-methoxy-,(16-alpha,17-beta)-estra-3
• 3,17BETA-DIHYDROXY-1,3,5[10]-ESTRATRIENE 3-METHYL ETHER
• 3-3-BENZOYLOXY 17BETA-ESTROL
• Estriol EP Impurity C
• 1,3,5(10)-ESTRATRIEN-3,16-ALPHA, 17-BETA-TRIOL 3-METHYL ETHER
• 3,17B-ESTRADIOL 3-METHYL ETHER
• 5(10)-triene-16-alpha,17-beta-diol,3-methoxy-estra-3
• BETA-ESTRADIOL 3-METHYL ETHER
• 1,3,5(10)-ESTRATRIENE-3,16ALPHA,17BETA-TRIOL 3-METHYL ETHER

Estriol EP Impurity C

CAS: 1474-53-9

Formula: C₁₉H₂₆O₃

Color and Shape: White To Off-White Solid

Molecular weight: 302.41

Ref: 4Z-E-353

Estriol Methyl Ether

CAS: 1474-53-9

Impurity Estriol EP Impurity C Applications Estriol Methyl Ether (Estriol EP Impurity C) is a metabolite (1,2) of Estriol (E888960), which is a produced naturally and also a metabolite of Estradiol (E888000). Estriol is a GPR3 antagonist in estrogen receptor-negative breast cancer cells displaying anti-proliferative effects (3). References 1. Marrian, G. et al.: Biochem. J. 1929;23(5):1090-8.2. Rogerson, B. et al.: Arch. Biochem. Biophys. 1986 Oct;250(1):70-85.3. Lappano, R. et al.: Mol Cell Endocrinol. 2010 May 14;320(1-2):162-70.

Formula: C₁₉H₂₆O₃

Color and Shape: Neat

Molecular weight: 302.41

Ref: TR-E668660

Estriol EP Impurity C

Controlled Product

CAS: 1474-53-9

Formula: C₁₉H₂₆O₃

Color and Shape: Neat

Molecular weight: 302.41

Ref: 86-MM0130.01

Estriol EP Impurity C

CAS: 1474-53-9

Formula: C₁₉H₂₆O₃

Molecular weight: 302.4

Ref: ST-EA-CP-E28003