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CAS 147403-03-0

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Azilsartan

Description:
Azilsartan is an angiotensin II receptor antagonist primarily used in the treatment of hypertension. It belongs to the class of medications known as sartans, which work by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby lowering blood pressure. Azilsartan is characterized by its high selectivity for the angiotensin II type 1 receptor (AT1), which contributes to its efficacy in managing blood pressure. The compound is typically administered orally and is known for its long half-life, allowing for once-daily dosing. In addition to its antihypertensive effects, Azilsartan may have beneficial effects on renal function and cardiovascular health. Its chemical structure includes a biphenyl group and a carboxylic acid moiety, which are essential for its biological activity. As with other medications in its class, potential side effects may include dizziness, fatigue, and elevated potassium levels, necessitating monitoring during treatment. Overall, Azilsartan represents a valuable option in the pharmacological management of hypertension.
Formula:C25H20N4O5
InChI:InChI=1S/C25H20N4O5/c1-2-33-24-26-20-9-5-8-19(23(30)31)21(20)29(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-27-25(32)34-28-22/h3-13H,2,14H2,1H3,(H,30,31)(H,27,28,32)
InChI key:InChIKey=KGSXMPPBFPAXLY-UHFFFAOYSA-N
SMILES:C(N1C=2C(N=C1OCC)=CC=CC2C(O)=O)C3=CC=C(C=C3)C4=C(C=CC=C4)C5=NOC(=O)N5
Synonyms:
  • 1-[[2′-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid
  • 1H-Benzimidazole-7-carboxylic acid, 1-[[2′-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-
  • 2-Ethoxy-1-([4-[2-(5-oxo-2,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl)-1H-1,3-benzodiazole-7-carboxylic acid
  • 2-Ethoxy-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid
  • 2-Ethoxy-1-[[2′-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid
  • 2-Ethoxy-3-[[4-[2-(5-oxo-2H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
  • Azilva
  • Tak 536
  • Azilsartan
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Found 11 products.
  • Azilsartan

    CAS:
    Formula:C25H20N4O5
    Purity:>98.0%(T)(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:456.46

    Ref: 3B-A2601

    1g
    267.00€
    200mg
    81.00€
  • Azilsartan

    CAS:
    <p>Azilsartan (TAK-536) is an Angiotensin II Type 1 receptor antagonist that lowers blood pressure.</p>
    Formula:C25H20N4O5
    Purity:99.35% - 99.62%
    Color and Shape:Solid
    Molecular weight:456.45
  • Ref: IN-DA001EVU

    1g
    56.00€
    5g
    104.00€
    10g
    148.00€
    1kg
    To inquire
    25g
    230.00€
    10mg
    26.00€
    250g
    To inquire
    500g
    To inquire
    250mg
    33.00€
  • Azilsartan

    CAS:
    <p>Azilsartan</p>
    Purity:≥98%
    Molecular weight:456.45g/mol

    Ref: 54-BUP15789

    1g
    336.00€
    25mg
    53.00€
    50mg
    76.00€
    100mg
    122.00€
    200mg
    180.00€
    500mg
    273.00€
  • Azilsartan

    CAS:
    <p>Azilsartan</p>
    Purity:99%
    Molecular weight:456.45g/mol

    Ref: 54-OR1028885

    1g
    36.00€
    5g
    72.00€
    25g
    263.00€
    100g
    933.00€
    250mg
    32.00€
  • Azilsartan

    CAS:
    Formula:C25H20N4O5
    Color and Shape:White To Off-White Solid
    Molecular weight:456.46

    Ref: 4Z-A-841

    5mg
    To inquire
    10mg
    349.00€
    25mg
    444.00€
    50mg
    635.00€
    100mg
    To inquire
  • Azilsartan

    CAS:
    Color and Shape:Neat

    Ref: 86-MM3924.00

    250mg
    1,297.00€
  • Azilsartan

    Controlled Product
    CAS:
    <p>Applications Azilsartan is an analgesic and antiinflammatory drugs containing angiotensin II antagonists.<br>References Kohara, Y., et al.: J. Med. Chem., 39, 5228 (1996), Plomgaard, P., et al.: Diabetes, 54, 2939 (2005), Fenton, C., et al.: Drugs, 2005, 65, 537,<br></p>
    Formula:C25H20N4O5
    Color and Shape:White To Off-White
    Molecular weight:456.45

    Ref: TR-A926900

    10mg
    105.00€
    50mg
    138.00€
    250mg
    320.00€
  • Azilsartan - Bio-X ™

    CAS:
    <p>Azilsartan is an angiotensin II receptor blocker that is used to treat hypertension. It blocks the binding of angiotensin II receptors to the AT1 receptor by selectively binding to AT1 receptors as an antagonist, blocking the vasoconstrictor and aldosterone-secreting effects of angiotensin II.</p>
    Formula:C25H20N4O5
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:456.45 g/mol

    Ref: 3D-BA164233

    50mg
    135.00€
  • Azilsartan

    CAS:
    <p>Angiotensin II, type I receptor antagonist; anti-hypertensive</p>
    Formula:C25H20N4O5
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:456.45 g/mol

    Ref: 3D-FA18113

    2g
    185.00€
    5g
    277.00€
    10g
    347.00€
    25g
    617.00€
    50g
    877.00€
  • Azilsartan Impurity 100

    CAS:
    Formula:C25H20N4O5
    Molecular weight:456.46

    Ref: ST-EA-CP-A36115

    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire