CAS 147403-03-0
:Azilsartan
Description:
Azilsartan is an angiotensin II receptor antagonist primarily used in the treatment of hypertension. It belongs to the class of medications known as sartans, which work by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby lowering blood pressure. Azilsartan is characterized by its high selectivity for the angiotensin II type 1 receptor (AT1), which contributes to its efficacy in managing blood pressure. The compound is typically administered orally and is known for its long half-life, allowing for once-daily dosing. In addition to its antihypertensive effects, Azilsartan may have beneficial effects on renal function and cardiovascular health. Its chemical structure includes a biphenyl group and a carboxylic acid moiety, which are essential for its biological activity. As with other medications in its class, potential side effects may include dizziness, fatigue, and elevated potassium levels, necessitating monitoring during treatment. Overall, Azilsartan represents a valuable option in the pharmacological management of hypertension.
Formula:C25H20N4O5
InChI:InChI=1S/C25H20N4O5/c1-2-33-24-26-20-9-5-8-19(23(30)31)21(20)29(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-27-25(32)34-28-22/h3-13H,2,14H2,1H3,(H,30,31)(H,27,28,32)
InChI key:InChIKey=KGSXMPPBFPAXLY-UHFFFAOYSA-N
SMILES:C(N1C=2C(N=C1OCC)=CC=CC2C(O)=O)C3=CC=C(C=C3)C4=C(C=CC=C4)C5=NOC(=O)N5
Synonyms:- 1-[[2′-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid
- 1H-Benzimidazole-7-carboxylic acid, 1-[[2′-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-
- 2-Ethoxy-1-([4-[2-(5-oxo-2,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl)-1H-1,3-benzodiazole-7-carboxylic acid
- 2-Ethoxy-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid
- 2-Ethoxy-1-[[2′-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid
- 2-Ethoxy-3-[[4-[2-(5-oxo-2H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
- Azilva
- Tak 536
- Azilsartan
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Found 11 products.
1H-Benzimidazole-7-carboxylic acid, 1-[[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-
CAS:Formula:C25H20N4O5Purity:98%Color and Shape:SolidMolecular weight:456.4501Ref: IN-DA001EVU
1g56.00€5g104.00€10g148.00€1kgTo inquire25g230.00€10mg26.00€250gTo inquire500gTo inquire250mg33.00€Azilsartan
CAS:Azilsartan (TAK-536) is an Angiotensin II Type 1 receptor antagonist that lowers blood pressure.Formula:C25H20N4O5Purity:99.35% - 99.62%Color and Shape:SolidMolecular weight:456.45Azilsartan
CAS:Formula:C25H20N4O5Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:456.46Azilsartan
CAS:Controlled ProductApplications Azilsartan is an analgesic and antiinflammatory drugs containing angiotensin II antagonists.
References Kohara, Y., et al.: J. Med. Chem., 39, 5228 (1996), Plomgaard, P., et al.: Diabetes, 54, 2939 (2005), Fenton, C., et al.: Drugs, 2005, 65, 537,Formula:C25H20N4O5Color and Shape:White To Off-WhiteMolecular weight:456.45Azilsartan - Bio-X ™
CAS:Azilsartan is an angiotensin II receptor blocker that is used to treat hypertension. It blocks the binding of angiotensin II receptors to the AT1 receptor by selectively binding to AT1 receptors as an antagonist, blocking the vasoconstrictor and aldosterone-secreting effects of angiotensin II.
Formula:C25H20N4O5Purity:Min. 95%Color and Shape:PowderMolecular weight:456.45 g/molAzilsartan
CAS:Angiotensin II, type I receptor antagonist; anti-hypertensive
Formula:C25H20N4O5Purity:Min. 95%Color and Shape:PowderMolecular weight:456.45 g/molRef: 3D-FA18113
Discontinued product
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