CAS 147403-03-0: Azilsartan

Description: Azilsartan is an angiotensin II receptor antagonist primarily used in the treatment of hypertension. It belongs to the class of medications known as sartans, which work by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby lowering blood pressure. Azilsartan is characterized by its high selectivity for the angiotensin II type 1 receptor (AT1), which contributes to its efficacy in managing blood pressure. The compound is typically administered orally and is known for its long half-life, allowing for once-daily dosing. In addition to its antihypertensive effects, Azilsartan may have beneficial effects on renal function and cardiovascular health. Its chemical structure includes a biphenyl group and a carboxylic acid moiety, which are essential for its biological activity. As with other medications in its class, potential side effects may include dizziness, fatigue, and elevated potassium levels, necessitating monitoring during treatment. Overall, Azilsartan represents a valuable option in the pharmacological management of hypertension.

Formula: C₂₅H₂₀N₄O₅

InChI: InChI=1S/C25H20N4O5/c1-2-33-24-26-20-9-5-8-19(23(30)31)21(20)29(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-27-25(32)34-28-22/h3-13H,2,14H2,1H3,(H,30,31)(H,27,28,32)

InChI key: InChIKey=KGSXMPPBFPAXLY-UHFFFAOYSA-N

SMILES: O=C(O)C1=CC=CC=2N=C(OCC)N(C21)CC=3C=CC(=CC3)C=4C=CC=CC4C5=NOC(=O)N5

Synonyms:

• 1-[[2′-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid
• 1H-Benzimidazole-7-carboxylic acid, 1-[[2′-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-
• 2-Ethoxy-1-([4-[2-(5-oxo-2,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl)-1H-1,3-benzodiazole-7-carboxylic acid
• 2-Ethoxy-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid
• 2-Ethoxy-1-[[2′-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid
• 2-Ethoxy-3-[[4-[2-(5-oxo-2H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
• Azilva
• Tak 536
• Azilsartan

Azilsartan

CAS: 147403-03-0

• Formula: C₂₅H₂₀N₄O₅
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 456.46

Azilsartan

CAS: 147403-03-0

Azilsartan (TAK-536) is an Angiotensin II Type 1 receptor antagonist that lowers blood pressure.

• Formula: C₂₅H₂₀N₄O₅
• Purity: 99.35% - 99.62%
• Color and Shape: Solid
• Molecular weight: 456.45

1H-Benzimidazole-7-carboxylic acid, 1-[[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-

CAS: 147403-03-0

• Formula: C₂₅H₂₀N₄O₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 456.4501

Azilsartan

CAS: 147403-03-0

• Formula: C₂₅H₂₀N₄O₅
• Color and Shape: White To Off-White Solid
• Molecular weight: 456.46

Azilsartan

CAS: 147403-03-0

• Purity: 99%
• Molecular weight: 456.45g/mol

Azilsartan

CAS: 147403-03-0

• Formula: C₂₅H₂₀N₄O₅
• Color and Shape: Neat
• Molecular weight: 456.45

Azilsartan

CAS: 147403-03-0

Applications Azilsartan is an analgesic and antiinflammatory drugs containing angiotensin II antagonists. References Kohara, Y., …

• Formula: C₂₅H₂₀N₄O₅
• Color and Shape: White To Off-White
• Molecular weight: 456.45

Azilsartan

CAS: 147403-03-0

Angiotensin II, type I receptor antagonist; anti-hypertensive

• Formula: C₂₅H₂₀N₄O₅
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 456.45 g/mol

Azilsartan - Bio-X ™

CAS: 147403-03-0

Azilsartan is an angiotensin II receptor blocker that is used to treat hypertension. It blocks …

• Formula: C₂₅H₂₀N₄O₅
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 456.45 g/mol