CAS 1474034-05-3

N-(2-Cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoropropanamide

Description:

N-(2-Cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoropropanamide is a synthetic organic compound characterized by its complex structure, which includes a noroleanane skeleton, a cyano group, and a difluoropropanamide moiety. This compound features multiple functional groups, including carbonyls and a cyano group, which contribute to its reactivity and potential biological activity. The presence of fluorine atoms in the difluoropropanamide portion may enhance lipophilicity and metabolic stability, making it of interest in medicinal chemistry. The compound's unique structural features suggest potential applications in drug development, particularly in targeting specific biological pathways. Its synthesis and characterization would typically involve advanced organic chemistry techniques, including spectroscopic methods for structural elucidation. As with many synthetic compounds, understanding its pharmacokinetics, toxicity, and biological interactions would be crucial for evaluating its potential therapeutic uses. Further research is necessary to explore its full range of properties and applications in various fields, including pharmaceuticals and agrochemicals.

Formula: C₃₃H₄₄F₂N₂O₃

InChI: InChI=1S/C33H44F2N2O3/c1-27(2)11-13-33(37-26(40)32(8,34)35)14-12-31(7)24(20(33)17-27)21(38)15-23-29(5)16-19(18-36)25(39)28(3,4)22(29)9-10-30(23,31)6/h15-16,20,22,24H,9-14,17H2,1-8H3,(H,37,40)/t20-,22-,24-,29-,30+,31+,33-/m0/s1

InChI key: InChIKey=RJCWBNBKOKFWNY-IDPLTSGASA-N

SMILES: N(C(C(C)(F)F)=O)[C@]12[C@]([C@@]3([C@@](C)(CC1)[C@@]4(C)C(=CC3=O)[C@]5(C)[C@@](CC4)(C(C)(C)C(=O)C(C#N)=C5)[H])[H])(CC(C)(C)CC2)[H]

Synonyms:

• Skyclarys
• N-(2-Cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoropropanamide
• Omaveloxolone
• Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-
• RTA 408

Omaveloxolone

CAS: 1474034-05-3

Purity: 99.40%

Molecular weight: 554.723

Ref: 10-F979543

Nrf1-activator-1

CAS: 1474034-05-3

Formula: C₃₃H₄₄F₂N₂O₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 554.7109

Ref: IN-DA00ABL1

N-((4As,6Ar,6Bs,8Ar,12As,14Ar,14Bs)-11-Cyano-2,2,6A,6B,9,9,12A-Heptamethyl-10,14-Dioxo-1,3,4,5,6,6A,6B,7,8,8A,9,10,12A,14,14A,14B-Hexadecahydropicen-4A(2H)-Yl)-2,2-Difluoropropanamide

CAS: 1474034-05-3

N-((4As,6Ar,6Bs,8Ar,12As,14Ar,14Bs)-11-Cyano-2,2,6A,6B,9,9,12A-Heptamethyl-10,14-Dioxo-1,3,4,5,6,6A,6B,7,8,8A,9,10,12A,14,14A,14B-Hexadecahydropicen-4A(2H)-Yl)-2,2-Difluoropropanamide

Purity: 99%

Molecular weight: 554.71g/mol

Ref: 54-PC108762

Omaveloxolone

CAS: 1474034-05-3

Omaveloxolone

Purity: ≥98%

Molecular weight: 554.71g/mol

Ref: 54-BUP07563

Omaveloxolone

CAS: 1474034-05-3

Omaveloxolone (RTA-408) (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.

Formula: C₃₃H₄₄F₂N₂O₃

Purity: 98.7% - 99.92%

Color and Shape: Solid

Molecular weight: 554.71

Ref: TM-T6919

RTA 408-d3

Controlled Product

CAS: 1474034-05-3

Formula: C₃₃D₃H₄₁F₂N₂O₃

Color and Shape: Neat

Molecular weight: 557.729

Ref: TR-R700992