CAS 147404-72-6

4'-(Bromomethyl)biphenyl-2-carboxamide

Description:

4'-(Bromomethyl)biphenyl-2-carboxamide, with the CAS number 147404-72-6, is an organic compound characterized by its biphenyl structure, which consists of two phenyl rings connected by a single bond. The presence of a bromomethyl group (-CH2Br) at the para position relative to the carboxamide functional group (-C(=O)NH2) introduces both halogen and functional group reactivity, making it a versatile intermediate in organic synthesis. This compound typically exhibits moderate solubility in organic solvents, reflecting its hydrophobic biphenyl backbone, while the carboxamide group can engage in hydrogen bonding, influencing its physical properties. The bromine atom can participate in nucleophilic substitution reactions, allowing for further functionalization. Additionally, the compound may exhibit biological activity, making it of interest in medicinal chemistry. Its stability under standard conditions is generally good, although it should be handled with care due to the presence of the bromine atom, which can pose health risks. Overall, 4'-(Bromomethyl)biphenyl-2-carboxamide serves as a valuable building block in various chemical applications.

Formula: C₁₄H₁₂BrNO

InChI: InChI=1/C14H12BrNO/c15-9-10-5-7-11(8-6-10)12-3-1-2-4-13(12)14(16)17/h1-8H,9H2,(H2,16,17)

SMILES: c1ccc(c(c1)c1ccc(cc1)CBr)C(=N)O

Synonyms:

• 4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide
• Telmisartan Impurity 17
• TelMisartan-BroMo AMide IMpurity
• Telmisartan Bromo Amide
• 4'-(Bromomethyl)biphenyl-2-carboxamide
• Telmisartan impurity 4'-(bromomethyl)biphenyl-2-carboxamide
• 2-[4-(broMoMethyl)phenyl]benzaMide
• [1,1'-Biphenyl]-2-carboxamide, 4'-(bromomethyl)-

[1,1'-Biphenyl]-2-carboxamide, 4'-(bromomethyl)-

CAS: 147404-72-6

Formula: C₁₄H₁₂BrNO

Purity: 95%

Color and Shape: Solid

Molecular weight: 290.1552

Ref: IN-DA001EVQ

4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide

CAS: 147404-72-6

4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide

Purity: 95%

Molecular weight: 290.16g/mol

Ref: 54-OR1044429

Telmisartan Impurity 14

CAS: 147404-72-6

Formula: C₁₄H₁₂BrNO

Color and Shape: White To Off-White Solid

Molecular weight: 290.16

Ref: 4Z-T-1313

4'-(Bromomethyl)[1,1'-biphenyl]-2-carboxamide

CAS: 147404-72-6

Color and Shape: Neat

Ref: 86-MM0939.20

4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide

Controlled Product

CAS: 147404-72-6

Impurity Telmisartan Bromo Amide Impurity
Applications An impurity in the preparation of the angiotensin II receptor antagonist Telmisartan (T017000).
References Wienen, W., et al.: Brit. J. Pharmacol., 110, 245 (1993), Neutel, J.M., and Smith, D.H.G.: Adv. Ther., 15, 206 (1998)

Formula: C₁₄H₁₂BrNO

Color and Shape: White

Molecular weight: 290.16

Ref: TR-B685270

4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide

CAS: 147404-72-6

4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide is a custom synthesis drug product. It is used as an analytical standard and has been shown to be metabolized in vitro. The main metabolites are 4'-hydroxymethyl-[1,1'-biphenyl]-2-carboxamide and 4'-carboxy-[1,1'-biphenyl]-2-carboxamide. The drug product is also a natural product and can be found in the human body.

Formula: C₁₄H₁₂BrNO

Purity: Min. 95%

Molecular weight: 290.16 g/mol

Ref: 3D-IB19246

Telmisartan Bromoamide Impurity

CAS: 147404-72-6

Formula: C₁₄H₁₂BrNO

Molecular weight: 290.16

Ref: ST-EA-CP-T4019