CAS 147432-77-7

ontazolast

Description:

Ontazolast, with the CAS number 147432-77-7, is a chemical compound that belongs to the class of drugs known as anti-inflammatory agents. It is primarily recognized for its role as a selective inhibitor of phosphodiesterase, which plays a crucial part in modulating cellular signaling pathways. The compound exhibits properties that can help in the treatment of various inflammatory conditions by reducing the levels of pro-inflammatory mediators. Ontazolast is characterized by its ability to enhance the levels of cyclic nucleotides, leading to vasodilation and inhibition of platelet aggregation. Additionally, it has been studied for its potential therapeutic effects in respiratory diseases, particularly asthma, due to its bronchodilator properties. The compound's pharmacokinetics, including absorption, distribution, metabolism, and excretion, are essential for understanding its efficacy and safety profile. As with many pharmaceutical agents, ontazolast's clinical applications and effectiveness are subject to ongoing research and evaluation.

Formula: C₂₁H₂₅N₃O

InChI: InChI=1/C21H25N3O/c1-15-10-11-20-19(13-15)24-21(25-20)23-18(17-9-5-6-12-22-17)14-16-7-3-2-4-8-16/h5-6,9-13,16,18H,2-4,7-8,14H2,1H3,(H,23,24)/t18-/m0/s1

SMILES: Cc1ccc2c(c1)[nH]c(=N[C@@H](CC1CCCCC1)c1ccccn1)o2

Synonyms:

• Ontazolast [USAN:INN]
• Birm 270
• 2-(((S)-2-Cyclohexyl-1-(2-pyridyl)ethyl)amino)-5-methylbenzoxazole
• 2-Benzoxazolamine, N-(2-cyclohexyl-1-(2-pyridinyl)ethyl)-5-methyl-, (S)-
• Unii-8P8Tw6B25I
• N-[(1S)-2-cyclohexyl-1-(pyridin-2-yl)ethyl]-5-methyl-1,3-benzoxazol-2-amine

Ontazolast

CAS: 147432-77-7

Ontazolast

Purity: ≥98%

Molecular weight: 335.44g/mol

Ref: 54-BUP03948

Ontazolast

CAS: 147432-77-7

Ontazolast: a small-molecule LTB4R antagonist targeting asthma and immune disorders.

Formula: C₂₁H₂₅N₃O

Purity: 99.79%

Color and Shape: Soild

Molecular weight: 335.44

Ref: TM-T68119

Ontazolast

Controlled Product

CAS: 147432-77-7

Applications Ontazolast is a leukotriene biosynthesis inhibitor.
References Lazer, E., et al.: J. Med. Chem., 37, 913 (1994); Hauss, D., et al.: J. Pharm. Sci., 87, 164 (1998);

Formula: C₂₁H₂₅N₃O

Color and Shape: Neat

Molecular weight: 335.443

Ref: TR-O656505

Ontazolast

CAS: 147432-77-7

Ontazolast is a positive allosteric modulator of the benzodiazepine site of the GABA A receptor. It is used in research to study protein interactions and to improve our understanding of the function of ion channels. Ontazolast is not intended for use as a therapeutic agent, but it can be used as a research tool.

Formula: C₂₁H₂₅N₃O

Purity: Min. 95%

Molecular weight: 335.40 g/mol

Ref: 3D-XFA43277