CAS 147438-27-5

2-Piperidinecarboxylicacid,1-[2-oxo-2-[(2R,3R,6S)-tetrahydro-2-hydroxy-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19E,21R)-14-hydroxy-22-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15,19-docosapentaen

Description:

2-Piperidinecarboxylic acid, 1-[2-oxo-2-[(2R,3R,6S)-tetrahydro-2-hydroxy-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19E,21R)-14-hydroxy-22-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15,19-docosapentaen] is a complex organic compound characterized by its intricate structure, which includes multiple functional groups such as carboxylic acids, ketones, and hydroxyl groups. This compound features a piperidine ring, contributing to its cyclic nature and potential biological activity. The presence of multiple stereocenters indicates that it may exhibit stereoisomerism, which can significantly influence its chemical behavior and interactions. The long hydrocarbon chain and various substituents suggest that it may possess lipophilic properties, potentially affecting its solubility and permeability in biological systems. Given its structural complexity, this compound may be of interest in medicinal chemistry and pharmacology, particularly in the development of novel therapeutic agents. Its CAS number, 147438-27-5, allows for precise identification in chemical databases and literature.

Formula: C₅₁H₇₉NO₁₃

Synonyms:

• 2-Piperidinecarboxylicacid, 1-[oxo[(2R,3R,6S)-tetrahydro-2-hydroxy-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19E,21R)-14-hydroxy-22-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15,19-docosapentaenyl]-3-methyl-2H-pyran-2-yl]acetyl]-(9CI)
• 2-Piperidinecarboxylic acid,1-[oxo[tetrahydro-2-hydroxy-6-[14-hydroxy-22-(4-hydroxy-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15,19-docosapentaenyl]-3-methyl-2H-pyran-2-yl]acetyl]-,[2R-[2a,2(S*),3a,6b[2S*,3E,5E,7E,9S*,11R*,13R*,14R*,15E,17R*,19E,21R*,22(1S*,3R*,4R*)]]]-
• Secorapamycin A

Seco Rapamycin

CAS: 147438-27-5

Seco Rapamycin, a ring-opened Rapamycin derivative, does not affect mTOR function.

Formula: C₅₁H₇₉NO₁₃

Color and Shape: Solid

Molecular weight: 914.187

Ref: TM-T38963

Rapamycin Impurity 5 (Seco Rapamycin)

CAS: 147438-27-5

Formula: C₅₁H₇₉NO₁₃

Color and Shape: White To Off-White Solid

Molecular weight: 914.19

Ref: 4Z-R-1810

Secorapamycin A

CAS: 147438-27-5

Secorapamycin A is a small molecule activator of the protein tyrosine phosphatase-1b (PTP-1B). Secorapamycin A binds to PTP-1B and increases its activity, resulting in inhibition of the nuclear factor kappa B (NF-κB) pathway. Secorapamycin A has been shown to inhibit ion channels, such as potassium channels, and to bind to antibodies. This drug also binds to receptors, including ligand binding domain on the human epidermal growth factor receptor 2 (HER2), which is expressed in some breast cancer cells. Secorapamycin A has also been found to inhibit cell proliferation by inhibiting protein synthesis.

Formula: C₅₁H₇₉NO₁₃

Purity: Min. 95%

Molecular weight: 914.2 g/mol

Ref: 3D-XFA43827

Seco Rapamycin

CAS: 147438-27-5

Formula: C₅₁H₇₉NO₁₃

Molecular weight: 914.19

Ref: ST-EA-CP-R26008