CAS 147526-32-7: Pitavastatin calcium

Description:Pitavastatin calcium is a synthetic lipid-lowering agent belonging to the statin class, primarily used to manage hyperlipidemia and reduce the risk of cardiovascular disease. It functions by inhibiting HMG-CoA reductase, an enzyme crucial for cholesterol biosynthesis in the liver, thereby lowering levels of low-density lipoprotein (LDL) cholesterol and triglycerides while modestly increasing high-density lipoprotein (HDL) cholesterol. The compound is characterized by its calcium salt form, which enhances its solubility and bioavailability. Pitavastatin is typically administered orally and exhibits a relatively long half-life, allowing for once-daily dosing. It is known for its favorable pharmacokinetic profile, including minimal drug-drug interactions compared to other statins. Common side effects may include muscle pain, gastrointestinal disturbances, and liver enzyme elevations, necessitating monitoring during treatment. As with other statins, it is contraindicated in certain populations, such as those with active liver disease or during pregnancy. Overall, Pitavastatin calcium is an effective option in the management of dyslipidemia, contributing to improved cardiovascular health outcomes.

Formula:C₂₅H₂₄FNO₄Ca

InChI:InChI=1S/C25H24FNO4.Ca/c26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/b12-11+;/t18-,19-;/m1./s1

InChI key:InChIKey=AMUDYCAFPCQTAZ-NRFPMOEYSA-N

SMILES:[Ca].O=C(O)CC(O)CC(O)C=CC=1C(=NC=2C=CC=CC2C1C=3C=CC(F)=CC3)C4CC4

Synonyms:
(+)-Monocalciumbis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-,5-dihydroxy-6-heptenoate}
(+)-Monocalciumbis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoate}
(E)-(3R,5S)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid hemicalcium salt
6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6E)-
6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, calcium salt (2:1), [S-[R*,S*-(E)]]-
Calcium (E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate
Flovas
Livalo
NK 104 (acid)
Nk 104
See more synonyms
Pitava
Pitava 1
Pitavastatin hemicalcium
calcium bis{(1R,3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-1,3,5-trihydroxyhept-6-en-1-olate}

Found 10 products.

Product data	Purity	Price range	Estimated delivery
Pitavastatin Calcium (contains 15% Water at maximum) REF: 3B-P2071CAS: 147526-32-7	>98.0%(T)(HPLC)	189.00 €	Fri 04 Apr 25
6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6E)- REF: IN-DA001EYECAS: 147526-32-7	98%	To inquire	Fri 11 Apr 25
Pitavastatin calcium REF: 54-IN12073CAS: 147526-32-7	98%	32.00 €~3,129.00 €	Mon 14 Apr 25
Pitavastatin Calcium Salt REF: 4Z-P-641CAS: 147526-32-7	- - -	To inquire	Mon 14 Apr 25
Pitavastatin-d4 Calcium Salt REF: 4Z-P-645CAS: 147526-32-7	- - -	To inquire	Mon 14 Apr 25
Pitavastatin calcium salt REF: 7W-GP8116CAS: 147526-32-7	≥ 98.0% (anhydrous basis)	59.00 €	Mon 14 Apr 25
Pitavastatin Calcium REF: 86-MM3741.00CAS: 147526-32-7	- - -	1,816.00 €	Mon 14 Apr 25
Pitavastatin calcium REF: TM-T2534CAS: 147526-32-7	100% - 99.49%	40.00 €~227.00 €	Mon 21 Apr 25
Pitavastatin Calcium REF: TR-P531000CAS: 147526-32-7	- - -	101.00 €~556.00 €	Mon 21 Apr 25
Pitavastatin calcium REF: 3D-FP37016CAS: 147526-32-7	Min. 95%	143.00 €~1,003.00 €	Tue 22 Apr 25