CAS 1476-82-0

1-(beta-D-ribofuranosyl)-1,3,5-triazine-2,4(1H,3H)-dione

Description:

1-(beta-D-ribofuranosyl)-1,3,5-triazine-2,4(1H,3H)-dione, commonly referred to as ribavirin, is a nucleoside analog with antiviral properties. This compound features a triazine ring structure, which is a six-membered heterocyclic ring containing three nitrogen atoms and three carbon atoms. The presence of the beta-D-ribofuranosyl moiety indicates that it is a ribose sugar derivative, contributing to its biological activity. Ribavirin is known for its role in the treatment of viral infections, particularly in combination therapies for hepatitis C and certain viral hemorrhagic fevers. The compound exhibits a broad spectrum of antiviral activity by interfering with viral RNA synthesis and promoting mutagenesis in viral genomes. It is typically administered orally and is characterized by moderate solubility in water. Ribavirin's mechanism of action involves the inhibition of viral replication, making it a valuable therapeutic agent in virology. However, it is important to note that ribavirin can have side effects and contraindications, necessitating careful medical supervision during its use.

Formula: C₈H₁₁N₃O₆

InChI: InChI=1/C8H11N3O6/c12-1-3-4(13)5(14)6(17-3)11-2-9-7(15)10-8(11)16/h2-6,12-14H,1H2,(H,10,15,16)/t3-,4-,5-,6-/m1/s1

SMILES: C([C@@H]1[C@H]([C@H]([C@H](n2cnc(nc2=O)O)O1)O)O)O

Synonyms:

• 1,3,5-Triazine-2,4(1H,3H)-dione, 1-beta-D-ribofuranosyl-

1-β-D-Ribofuranosyl-1,3,5-triazine-2,4(1H,3H)-dione

CAS: 1476-82-0

Formula: C₈H₁₁N₃O₆

Purity: 97%

Molecular weight: 245.1894

Ref: IN-DA00B0NC

1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazine-2,4(1H,3H)-dione

CAS: 1476-82-0

1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazine-2,4(1H,3H)-dione

Purity: 97%

Molecular weight: 245.19g/mol

Ref: 54-OR1074234

Uridine Impurity 5 (5-Aza-Uridine)

CAS: 1476-82-0

Formula: C₈H₁₁N₃O₆

Molecular weight: 245.19

Ref: 4Z-U-0141

5-Azauridine

Controlled Product

CAS: 1476-82-0

Applications 5-Azauridine (cas# 1476-82-0) is a useful research chemical.

Formula: C₈H₁₁N₃O₆

Color and Shape: Neat

Molecular weight: 245.189

Ref: TR-A805115

5-Azauridine

CAS: 1476-82-0

5-Azauridine is a nucleoside that is synthesized from uridine. It inhibits protein synthesis by inhibiting the enzyme orotate phosphoribosyltransferase. This enzyme converts orotic acid to orotidine 5′-monophosphate, which is a precursor for the synthesis of pyrimidines and purines. 5-Azauridine has been shown to have an inhibitory effect on leukemia cells in tissue culture and also has been shown to inhibit leukemic mice with an efficacy of 50%. This drug may be useful for the treatment of solid tumours as it inhibits protein synthesis.

Formula: C₈H₁₁N₃O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 245.19 g/mol

Ref: 3D-NA145615

5-Aza-Uridine

CAS: 1476-82-0

Formula: C₈H₁₁N₃O₆

Molecular weight: 245.19

Ref: ST-EA-CP-U6037