CAS 1477-19-6

Benzarone

Description:

Benzarone, with the CAS number 1477-19-6, is a chemical compound that belongs to the class of benzophenones. It is primarily recognized for its application as a pharmaceutical intermediate and in the synthesis of various organic compounds. Benzarone typically exhibits a crystalline solid form and is characterized by its aromatic structure, which contributes to its stability and reactivity. The compound is known for its potential use in photoprotection due to its ability to absorb ultraviolet light, making it relevant in cosmetic formulations. Additionally, it may possess antioxidant properties, which can be beneficial in various applications. However, like many organic compounds, it should be handled with care, as it may pose health risks if ingested or improperly managed. Its solubility characteristics can vary, often being more soluble in organic solvents than in water. Overall, Benzarone's unique chemical properties make it a valuable substance in both industrial and research settings.

Formula: C₁₇H₁₄O₃

InChI: InChI=1S/C17H14O3/c1-2-14-16(13-5-3-4-6-15(13)20-14)17(19)11-7-9-12(18)10-8-11/h3-10,18H,2H2,1H3

InChI key: InChIKey=RFRXIWQYSOIBDI-UHFFFAOYSA-N

SMILES: C(=O)(C=1C=2C(OC1CC)=CC=CC2)C3=CC=C(O)C=C3

Synonyms:

• (2-Ethyl-1-Benzofuran-3-Yl)(4-Hydroxyphenyl)Methanone
• (2-Ethyl-3-benzofuranyl)(4-hydroxyphenyl)methanone
• (2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone
• 2-Ethyl-3-(4-hydroxybenzoyl)benzofuran
• 2-Ethyl-3-(p-hydroxybenzoyl)benzofuran
• 2-Ethyl-3-benzofuranyl p-hydroxyphenyl ketone
• 2-Ethyl-3-p-hydroxybenzoylbenzofuran
• 2-Ethyl-4′-hydroxy-3-benzoylbenzofuran
• Benzaron
• Fagivil
• Fragivil
• Fragivix
• Ketone, 2-ethyl-3-benzofuranyl p-hydroxyphenyl
• L 2179-Labaz
• L 2197
• Methanone, (2-ethyl-3-benzofuranyl)(4-hydroxyphenyl)-
• NSC 82134

BENZARONE CRS

CAS: 1477-19-6

BENZARONE CRS

Formula: C₁₇H₁₄O₃

Molecular weight: 266.2913

Ref: 41-B0490000

Methanone, (2-​ethyl-​3-​benzofuranyl)​(4-​hydroxyphenyl)​-

CAS: 1477-19-6

Formula: C₁₇H₁₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 266.2913

Ref: IN-DA001F48

Benzarone

CAS: 1477-19-6

Benzarone

Purity: ≥98%

Molecular weight: 266.29g/mol

Ref: 54-BUP18284

(2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone (Benzarone)

Controlled Product

CAS: 1477-19-6

Formula: C₁₇H₁₄O₃

Color and Shape: Neat

Molecular weight: 266.29

Ref: 86-MM0456.03

(2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone

CAS: 1477-19-6

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 266.2959899902344

Ref: 10-F242155

Benzarone

CAS: 1477-19-6

Formula: C₁₇H₁₄O₃

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 266.30

Ref: 3B-E1289

Benzarone

CAS: 1477-19-6

Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.

Formula: C₁₇H₁₄O₃

Purity: 99.77%

Color and Shape: Solid

Molecular weight: 266.29

Ref: TM-T20545

Benzarone

Controlled Product

CAS: 1477-19-6

Applications Benzarone is an EYA (Eyes Absents), multifunctional protein involved in organogenesis, inhibitor which makes it a potent anticancer agent. EYA’s are over expressed in ovarian and breast cancers. As well it is involved in the synthesis of Human Uric Acid Transporter 1 inhibitors which may be used to treat kidney diseases.
References Tadjuidje, E. et al.: PLoS One., 7, 34806 (2012); M, Wempe, et al.: J. Med. Chem., 54, 2701 (2011);

Formula: C₁₇H₁₄O₃

Color and Shape: Neat

Molecular weight: 266.29

Ref: TR-B185150

Benzbromarone EP Impurity C

CAS: 1477-19-6

Formula: C₁₇H₁₄O₃

Molecular weight: 266.3

Ref: ST-EA-CP-B46003