CAS 1477-57-2

N,N′-1,8-Octanediylbis[2,2-dichloroacetamide]

Description:

N,N′-1,8-Octanediylbis[2,2-dichloroacetamide], with the CAS number 1477-57-2, is a chemical compound characterized by its amide functional groups and a long hydrocarbon chain. This substance features two 2,2-dichloroacetamide moieties linked by an octanediyl (C8) spacer, which contributes to its unique properties. It is typically a solid at room temperature and is known for its applications in various fields, including agriculture as a pesticide or herbicide, due to its ability to disrupt biological processes in target organisms. The presence of chlorine atoms enhances its reactivity and potential for biological activity. Additionally, the long hydrocarbon chain may impart hydrophobic characteristics, influencing its solubility and interaction with biological membranes. Safety considerations are important when handling this compound, as it may pose environmental and health risks, necessitating proper protective measures and disposal protocols. Overall, N,N′-1,8-Octanediylbis[2,2-dichloroacetamide] exemplifies a class of chemicals that combine structural complexity with functional utility.

Formula: C₁₂H₂₀Cl₄N₂O₂

InChI: InChI=1/C12H20Cl4N2O2/c13-9(14)11(19)17-7-5-3-1-2-4-6-8-18-12(20)10(15)16/h9-10H,1-8H2,(H,17,19)(H,18,20)

InChI key: InChIKey=FAOMZVDZARKPFJ-UHFFFAOYSA-N

SMILES: N(C(C(Cl)Cl)=O)CCCCCCCCNC(C(Cl)Cl)=O

Synonyms:

• 2,2-Dichloro-N-[8-[(2,2-dichloroacetyl)amino]octyl]acetamide
• Acetamide, N,N′-1,8-octanediylbis[2,2-dichloro-
• Acetamide, N,N′-octamethylenebis[2,2-dichloro-
• Bis-Diamine
• Fertilysin
• Fertilysine
• N,N'-octane-1,8-diylbis(2,2-dichloroacetamide)
• N,N-Bis(dichloroacetyl)-1,8-octamethylenediamine
• N,N′-1,8-Octanediylbis[2,2-dichloroacetamide]
• N,N′-Bis(dichloroacetyl)-1,8-diaminooctane
• N,N′-Octamethylenebis(2,2-dichloroacetamide)
• NSC 59354
• Win 18441
• Win 18446
• N,N-Octamethylenebis(dichloroacetamide)
• win18,446
• n,n-bis(dichloroacetyl)-1,8-octanediamine
• n,n’,1,8-octanediylbis(2,2-dichloro-acetamid
• win18441
• win18446
• N,N'-(Octane-1,8-diyl)bis(2,2-dichloroacetaMide)
• r-010-tk
• N,N''-OCTMETHYLENEBIS (DICHLOROACETAMIDE)
• n,n’-octamethylenebis(2,2-dichloroactamide)
• N,N'-(1,8-Octanediyl)bis(2,2-dichloroacetamide)
• N,N'-OCTA-METHYLENE-BIS[2,2-DICHLOROACETAMIDE]
• N,N'-Octamethylenebis(dichloroacetamide),97%
• n,n’-octamethylenebis(2,2-dichloro-acetamid
• bisdiamine

Acetamide, N,N'-1,8-octanediylbis[2,2-dichloro-

CAS: 1477-57-2

Formula: C₁₂H₂₀Cl₄N₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 366.1114

Ref: IN-DA001F41

N,N’-(Octane-1,8-diyl)Bis(2,2-Dichloroacetamide)

CAS: 1477-57-2

N,N’-(Octane-1,8-diyl)Bis(2,2-Dichloroacetamide)

Purity: 97%

Molecular weight: 366.11g/mol

Ref: 54-OR1014078

WIN 18446

CAS: 1477-57-2

WIN 18446

Purity: ≥98%

Molecular weight: 366.11g/mol

Ref: 54-BUP14131

WIN 18446

CAS: 1477-57-2

inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)

Formula: C₁₂H₂₀Cl₄N₂O₂

Purity: 99.69%

Color and Shape: Solid

Molecular weight: 366.11

Ref: TM-T23533

N,N'-Octamethylenebis(dichloroacetamide)

CAS: 1477-57-2

Purity: 96.0%

Color and Shape: Solid

Molecular weight: 366.1000061035156

Ref: 10-F013680

Win 18446

Controlled Product

CAS: 1477-57-2

Applications Win 18446 was shown to inhibit the biosynthesis of retinoic acid from retinol in neonatal and adult murine testis and in the embryonic murine gonad.
References Hogarth, C.A., et al.: Biol. Reproduct., 84, 957 (2011);

Formula: C₁₂H₂₀Cl₄N₂O₂

Color and Shape: Neat

Molecular weight: 366.11

Ref: TR-W498820

WIN 18446

CAS: 1477-57-2

WIN 18446 is a contraceptive that belongs to the class of progestins. It has been shown to inhibit the proliferation of cardiac, bowel, and testicular mesenchymal cells in vitro. WIN 18446 also showed high resistance and low toxicity against cancer cell viability in experimental models. In addition, WIN 18446 has shown promising results as a potential treatment for autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. This drug has also been shown to have anti-inflammatory effects by inhibiting the activity of enzymes that cause inflammation, such as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX). Clinical studies have shown that WIN 18446 can be used to treat diaphragmatic hernia in rats with no side effects on liver function or weight gain.
WIN 18446 is not active against bacteria or viruses and does not affect the integrity of DNA.

Formula: C₁₂H₂₀Cl₄N₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 366.11 g/mol

Ref: 3D-FO155274