CAS 147700-11-6

8-(3-CHLOROSTYRYL) CAFFEINE A2A ADENOSIN E RECEPTO

Description:

8-(3-Chlorostyryl) caffeine, also known by its CAS number 147700-11-6, is a synthetic derivative of caffeine that exhibits unique pharmacological properties. This compound is characterized by the presence of a chlorostyryl group at the 8-position of the caffeine molecule, which enhances its interaction with adenosine receptors, particularly the A2A subtype. The structural modification contributes to its potential as a research tool in neuropharmacology, particularly in studies related to the modulation of neurotransmitter systems. The compound is typically analyzed using techniques such as NMR spectroscopy and mass spectrometry to confirm its structure and purity. Its biological activity may include effects on cognitive function, mood regulation, and potential therapeutic applications in conditions like Parkinson's disease or other neurodegenerative disorders. However, detailed studies on its efficacy, safety, and mechanism of action are essential for understanding its full potential in medicinal chemistry. As with many synthetic compounds, proper handling and safety measures should be observed due to potential toxicity or side effects.

Formula: C₁₆H₁₅ClN₄O₂

InChI: InChI=1/C16H15ClN4O2/c1-19-12(8-7-10-5-4-6-11(17)9-10)18-14-13(19)15(22)21(3)16(23)20(14)2/h4-9H,1-3H3/b8-7+

InChI key: InChIKey=WBWFIUAVMCNYPG-BQYQJAHWSA-N

SMILES: CN1C2=C(N=C1/C=C/C3=CC(Cl)=CC=C3)N(C)C(=O)N(C)C2=O

Synonyms:

• 1,3,7-Trimethyl-8-(3-chlorostyryl)xanthine, CSC
• 1H-Purine-2,6-dione, 8-[(1E)-2-(3-chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-
• 1H-Purine-2,6-dione, 8-[2-(3-chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-, (E)-
• 8-(3-Chlorostyryl)caffeine
• 8-[(1E)-2-(3-Chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
• 8-[(E)-2-(3-chlorophenyl)ethenyl]-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione
• 8-(3-CHLOROSTYRYL) CAFFEINE A2A ADENOSIN E RECEPTO
• 8-[2-(3-Chloro-phenyl)-vinyl]-1,3,7-trimethyl-3,7-dihydro-purine-2,6-dione
• (E)-8-[2-(3-Chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

1H-Purine-2,6-dione, 8-[(1E)-2-(3-chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-

CAS: 147700-11-6

Formula: C₁₆H₁₅ClN₄O₂

Molecular weight: 330.7689

Ref: IN-DA001F4S

8-(3-Chlorostyryl)caffeine

CAS: 147700-11-6

Formula: C₁₆H₁₅ClN₄O₂

Molecular weight: 330.77

Ref: 7W-GK6817

8-(3-Chlorostyryl)caffeine

Controlled Product

CAS: 147700-11-6

Formula: C₁₆H₁₅ClN₄O₂

Color and Shape: Neat

Molecular weight: 330.769

Ref: TR-C422013

8-(3-Chlorostyryl)caffeine

Controlled Product

CAS: 147700-11-6

8-(3-Chlorostyryl)caffeine is a caffeine derivative that binds to the adenosine A3 receptor. It has been shown to inhibit locomotor activity and increase diastolic pressure in knockout mice lacking the adenosine A3 receptor. 8-(3-Chlorostyryl)caffeine has also been shown to have inhibitory properties on cyclase, which is necessary for the production of cAMP, the second messenger in cells. This drug also inhibits dopamine release from neurons and hydrogen bond formation with DNA, protein, and other biomolecules. Lastly, 8-(3-Chlorostyryl)caffeine can bind to both A1 and A2A receptors as well as to dna binding sites.

Formula: C₁₆H₁₅ClN₄O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 330.77 g/mol

Ref: 3D-XFA70011