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CAS 147762-58-1

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(-)-N-Desmethyl Tramadol

Description:
(-)-N-Desmethyl Tramadol, with the CAS number 147762-58-1, is a chemical compound that is a metabolite of the analgesic tramadol. It is classified as an opioid analgesic, primarily known for its pain-relieving properties. The compound exhibits a dual mechanism of action: it acts as a weak μ-opioid receptor agonist and also inhibits the reuptake of norepinephrine and serotonin, contributing to its analgesic effects. (-)-N-Desmethyl Tramadol is typically a white to off-white crystalline powder and is soluble in organic solvents, though its solubility in water is limited. The compound has a relatively low toxicity profile compared to stronger opioids, but it can still lead to dependence and has potential for abuse. Its pharmacokinetics involve hepatic metabolism, and it is primarily excreted through the kidneys. Due to its pharmacological properties, it is important to handle this substance with care, adhering to regulations regarding controlled substances in various jurisdictions.
Formula:C15H23NO2
InChI:InChI=1/C15H23NO2/c1-16-11-13-6-3-4-9-15(13,17)12-7-5-8-14(10-12)18-2/h5,7-8,10,13,16-17H,3-4,6,9,11H2,1-2H3/t13-,15+/m1/s1
Synonyms:
  • cis-(-)-1-(3-Methoxyphenyl)-2-[(methylamino)methyl]-cyclohexanol
  • (1S,2S)-(-)-1-(3-Methoxyphenyl)-2-[(methylamino)methyl]-cyclohexanol
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