CAS 147852-78-6

EPI-TRIPTOLIDE

Description:

EPI-TRIPTOLIDE, with the CAS number 147852-78-6, is a synthetic derivative of triptolide, which is a natural compound derived from the plant Tripterygium wilfordii. This substance is known for its potential therapeutic properties, particularly in the fields of oncology and immunology. EPI-TRIPTOLIDE exhibits anti-inflammatory and anti-cancer activities, making it a subject of interest in drug development. Its mechanism of action often involves the inhibition of specific signaling pathways that are crucial for cell proliferation and survival. The compound is characterized by its complex molecular structure, which includes multiple functional groups that contribute to its biological activity. Additionally, EPI-TRIPTOLIDE has been studied for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, which are essential for understanding its efficacy and safety profile in clinical applications. As research continues, EPI-TRIPTOLIDE may offer insights into novel therapeutic strategies for various diseases.

Formula: C₂₀H₂₆O₇

InChI: InChI=1/C20H26O7/c1-8(2)18(24)13(21)14-20(27-14)17(3)5-4-9-10(7-25-15(9)22)11(17)6-12-19(20,26-12)16(18)23/h8,11-14,16,21,23-24H,4-7H2,1-3H3/t11-,12-,13-,14-,16+,17-,18-,19+,20+/m0/s1

Synonyms:

• Triptolide, Epi-

14-Epitriptolide

CAS: 147852-78-6

14-Epitriptolide is a diterpenoid epoxide, which is derived from the natural product triptolide. It originates from the plant species *Tripterygium wilfordii*, commonly known in traditional Chinese medicine. The mode of action of 14-Epitriptolide involves the inhibition of RNA polymerase II-mediated transcription, thereby interfering with transcriptional processes essential for cancer cell survival and proliferation. Additionally, it induces oxidative stress and disrupts cellular homeostasis.

Formula: C₂₀H₂₆O₇

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 378.42 g/mol

Ref: 3D-FE65706