CAS 147859-97-0

LHRH (lamprey III)

Description:

LHRH (lamprey III), with the CAS number 147859-97-0, is a synthetic peptide that serves as a gonadotropin-releasing hormone (GnRH) analog. It is derived from the lamprey species and plays a crucial role in the regulation of reproductive functions. This peptide is characterized by its ability to stimulate the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary gland, thereby influencing gonadal function and fertility. LHRH (lamprey III) exhibits a specific amino acid sequence that distinguishes it from other GnRH analogs, contributing to its unique biological activity. It is typically used in research settings to study reproductive physiology and has potential applications in reproductive health and endocrinology. The stability and potency of this peptide make it a valuable tool in both basic and applied research, particularly in understanding the mechanisms of hormone regulation and the development of therapeutic agents targeting reproductive disorders.

Formula: C₅₉H₇₄N₁₈O₁₄

Synonyms:

• Peforelin
• M.W. 1259.50 C59H74N18O14
• Pyr-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH2

LHRH (lamprey III)

CAS: 147859-97-0

Lamprey GnRH (also called peforelin) is a highly potent and specific FSH-releasing peptide that may enhance fertility in animals and humans. The peptide has found application in stimulating FSH release in swine. Peforelin surpasses GnRH in suppressing the growth of MDA-MB-231 and MCF-7 breast cancer cells. In comparison to other GnRH-III analogs, the peptide exhibits a superior antitumor activity.

Formula: C₅₉H₇₄N₁₈O₁₄

Purity: 98.2%

Color and Shape: White

Molecular weight: 1259.35

Ref: 01-4028403

LGnRH-III, lamprey

CAS: 147859-97-0

GnRH III triggers luteinizing and follicle-stimulating hormone release, part of the conserved GnRH family.

Formula: C₅₉H₇₄N₁₈O₁₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 1259.33

Ref: TM-TP1700

Peforelin Trifluoroacetic Acid Salt(>90%)

Controlled Product

CAS: 147859-97-0

Applications Peforelin is Gonadotrophin-releasing Hormone (GnRH), a neuropeptides secreted by the hypothalamus that regulate reproduction in rats. It elicits Follicle-Stimulating Hormone (FSH) releasing activity in swine. Also it is identified in lampreys and possesses a hypothalamic role in reproduction.
References Ferris, J. K., et al.: J. Neuroendocrinol., 27, 772-786 (2015); Bruessow, K., et al.: Theriogenology, 74, 1570-1578 (2010); Sower, S. A., et al.: Gen. Comp. Endocrinol., 170, 276-282 (2011)

Formula: C₅₉H₇₄N₁₈O₁₄·C₂HF₃O₂

Purity: >90%

Color and Shape: Neat

Molecular weight: 1258.56319

Ref: TR-P218335