CAS 147923-08-8

3-(4-biphenylyl)-N-(tert-butoxycarbonyl)-L-alanin

Description:

3-(4-biphenylyl)-N-(tert-butoxycarbonyl)-L-alanin, with the CAS number 147923-08-8, is a chemical compound that belongs to the class of amino acids modified with a tert-butoxycarbonyl (Boc) protecting group. This compound features a biphenyl moiety, which contributes to its hydrophobic characteristics and may influence its interactions in biological systems. The presence of the Boc group provides stability and protects the amino group during synthetic processes, making it useful in peptide synthesis and drug development. The L-alanine backbone indicates that it is an optically active amino acid, which can participate in various biochemical reactions. Its structural characteristics suggest potential applications in medicinal chemistry, particularly in the design of peptide-based therapeutics. Additionally, the compound's solubility and reactivity can be influenced by the biphenyl substituent, which may affect its pharmacokinetic properties. Overall, this compound exemplifies the intersection of organic chemistry and biochemistry, highlighting the importance of functional groups in determining the behavior of amino acid derivatives.

Formula: C₂₁H₂₅NO₄

InChI: InChI=1/C21H25NO4/c1-21(2,3)26-20(25)22-18(19(24)14-23)13-15-9-11-17(12-10-15)16-7-5-4-6-8-16/h4-12,18,23H,13-14H2,1-3H3,(H,22,25)

SMILES: CC(C)(C)OC(=NC(Cc1ccc(cc1)c1ccccc1)C(=O)CO)O

Synonyms:

• 3-(4-Biphenylyl)-N-(tert-butoxycarbonyl)-L-alanine
• Boc-4-phenyl-Phe-OH
• Boc-Bip-OH
• Boc-L-4,4-Biphenylalanine
• tert-butyl N-[3-hydroxy-2-oxo-1-[(4-phenylphenyl)methyl]propyl]carbamate
• Boc-L-4,4'-Biphenylphenylalanine

N-(tert-Butoxycarbonyl)-4-phenyl-L-phenylalanine

CAS: 147923-08-8

Formula: C₂₀H₂₃NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 341.41

Ref: 3B-B4289

[1,​1'-​Biphenyl]​-​4-​propanoic acid, α-​[[(1,​1-​dimethylethoxy)​carbonyl]​amino]​-​, (αS)​-

CAS: 147923-08-8

Formula: C₂₀H₂₃NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 341.4009

Ref: IN-DA001FAN

Boc-4-phenyl-Phe-OH

CAS: 147923-08-8

Molecular weight: 341.40

Ref: 7W-GM0640

4-Phenyl-L-phenylalanine, N-BOC protected

CAS: 147923-08-8

4-Phenyl-L-phenylalanine, N-BOC protected

Formula: C₂₀H₂₃NO₄

Purity: 98%

Color and Shape: white powder

Molecular weight: 341.40092g/mol

Ref: 54-OR14630

(S)-3-([1,1′-Biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid

CAS: 147923-08-8

Formula: C₂₀H₂₃NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 341.407

Ref: 10-F239938

N-Boc-4-phenyl-L-phenylalanine

Controlled Product

CAS: 147923-08-8

Applications N-Boc-4-phenyl-L-phenylalanine is a reactant used in the synthesis of novel phenylalanines derived diamides as factor XIa inhibitors used in the treatment.
References Smith, L. et al.: Bioorg. Med. Chem. Lett., 26, 472 (2016);

Formula: C₂₀H₂₃NO₄

Color and Shape: Neat

Molecular weight: 341.4

Ref: TR-B642800

Boc-p-phenyl-L-Phenylalanine

CAS: 147923-08-8

Boc-p-phenyl-L-Phenylalanine is a protonated, chiral molecule that has been postulated to exist as an organophosphate. The compound is also known as p-phenyl-L-phenylalanine and is used in the synthesis of other compounds. Boc-p-phenyl-L-Phenylalanine can be synthesized from the homologues L-(+)-phenylethylamine and 2,2'-dibromoethanol. This compound has been shown to undergo solvating reactions with coordination complexes of metals such as copper and zinc. Experiments have shown that this molecule can exist in two configurations, enantiomers, which are mirror images of each other. The configuration of the molecule can be determined through experiments using NMR spectroscopy and by examining the shift of signals in proton nmr.

Formula: C₂₀H₂₃NO₄

Purity: Min. 95%

Molecular weight: 341.4 g/mol

Ref: 3D-FB47980