CymitQuimica logo

CAS 148-56-1

:

Flumethiazide

Description:
Flumethiazide is a thiazide diuretic commonly used in the treatment of hypertension and edema associated with various medical conditions. It functions by inhibiting sodium reabsorption in the distal convoluted tubule of the nephron, leading to increased excretion of sodium and water, thereby reducing blood volume and blood pressure. The chemical structure of flumethiazide includes a thiazide ring, which is characteristic of this class of diuretics, and it is typically administered in oral form. Flumethiazide is known for its relatively long duration of action compared to other diuretics, making it effective for managing chronic conditions. It may also have side effects, including electrolyte imbalances, particularly hypokalemia, and should be used with caution in patients with renal impairment. Additionally, it may interact with other medications, necessitating careful monitoring. Overall, flumethiazide is an important therapeutic agent in cardiovascular medicine, contributing to the management of fluid balance and blood pressure regulation.
Formula:C8H6F3N3O4S2
InChI:InChI=1S/C8H6F3N3O4S2/c9-8(10,11)4-1-5-7(2-6(4)19(12,15)16)20(17,18)14-3-13-5/h1-3H,(H,13,14)(H2,12,15,16)
InChI key:InChIKey=RGUQWGXAYZNLMI-UHFFFAOYSA-N
SMILES:O=S1(=O)C=2C(=CC(C(F)(F)F)=C(S(N)(=O)=O)C2)NC=N1
Synonyms:
  • 1-Hydroxy-6-(Trifluoromethyl)-1Lambda~4~,2,4-Benzothiadiazine-7-Sulfonamide 1-Oxide
  • 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-(trifluoromethyl)-, 1,1-dioxide
  • 6-(Trifluoromethyl)-1,4,2-benzothiadiazine-7-sulfonamido 1,1-dioxide
  • 6-(trifluoromethyl)-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
  • 6-Trifluoromethyl-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
  • 6-Trifluoromethyl-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide
  • 7-Sulfamoyl-6-trifluoromethyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
  • Ademil
  • Ademol
  • Fludemil
  • See more synonyms
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 2 products.