CAS 148-72-1

Pilocarpine nitrate

Description:

Pilocarpine nitrate is a chemical compound derived from pilocarpine, which is an alkaloid obtained from the leaves of the jaborandi plant. It is primarily known for its use in medicine, particularly in the treatment of glaucoma and dry mouth conditions. As a nitrate salt, pilocarpine nitrate is characterized by its solubility in water, which facilitates its administration in various pharmaceutical formulations. The compound acts as a muscarinic agonist, stimulating the parasympathetic nervous system, leading to increased salivation and lacrimation. In terms of physical properties, pilocarpine nitrate typically appears as a white to off-white crystalline powder. It is important to handle this substance with care, as it can cause side effects such as sweating, increased salivation, and gastrointestinal disturbances. Additionally, pilocarpine nitrate should be stored in a cool, dry place, away from light, to maintain its stability and efficacy. Overall, its pharmacological properties make it a valuable agent in therapeutic applications, particularly in ophthalmology and dentistry.

Formula: C₁₁H₁₆N₂O₂·HNO₃

InChI: InChI=1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1

InChI key: InChIKey=PRZXEPJJHQYOGF-GNAZCLTHSA-N

SMILES: N(=O)(=O)O.C([C@@H]1[C@H](CC)C(=O)OC1)C=2N(C)C=NC2

Synonyms:

• (3S)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one nitrate (1:1)
• (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one nitrate (1:1)
• 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, (3S,4R)-, mononitrate
• 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, (3S,4R)-, nitrate (1:1)
• 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, (3S-cis)-, mononitrate
• 3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one nitrate (1:1)
• Pilagan
• Pilocarpine Nitrate Usp
• Pilocarpine nitrate salt
• Pilocarpine subnitrate
• Pilocarpine, mononitrate
• Pilocarpinenitrate

PILOCARPINE NITRATE FOR SYSTEM SUITABILITY CRS

CAS: 148-72-1

PILOCARPINE NITRATE FOR SYSTEM SUITABILITY CRS

Formula: C₁₁H₁₆N₂O₂

Molecular weight: 208.2569

Ref: 41-Y0000106

Pilocarpine nitrate

CAS: 148-72-1

Pilocarpine nitrate

Formula: C₁₁H₁₆N₂O₂HNO₃

Purity: 98.9%

Color and Shape: White

Molecular weight: 271.11682

Ref: 47-503

PILOCARPINE NITRATE CRS

CAS: 148-72-1

PILOCARPINE NITRATE CRS

Formula: C₁₁H₁₆N₂O₂

Color and Shape: Crystalline Powder. White. Colourless. Powder.

Molecular weight: 208.2569

Ref: 41-P1700000

Pilocarpine Nitrate

CAS: 148-72-1

Other alkaloids,natural or reproduced by synthesis, and their salts, ethers,esters&other derivatives, nesoi

Formula: C₁₁H₁₆N₂O₂·HNO₃

Color and Shape: White Crystalline Powder

Molecular weight: 208.12118

Ref: 45-1539009

Pilocarpine nitrate

CAS: 148-72-1

Pilocarpine nitrate (Pilagan) is a slowly hydrolyzed muscarinic agonist with no nicotinic effects.

Formula: C₁₁H₁₆N₂O₂·HNO₃

Purity: 98% - 99.53%

Color and Shape: Solid

Molecular weight: 271.27

Ref: TM-T1231

Pilocarpine nitrate

CAS: 148-72-1

Formula: C₁₁H₁₆N₂O₂·HNO₃

Molecular weight: 271.27

Ref: 7W-GK8566

Pilocarpine Nitrate

CAS: 148-72-1

Formula: C₁₁H₁₆N₂O₂·HNO₃

Color and Shape: White To Off-White Solid

Molecular weight: 208.26 63.01

Ref: 4Z-P-771

Pilocarpine Nitrate

CAS: 148-72-1

Formula: C₁₁H₁₆N₂O₂·HNO₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 271.27

Ref: 3B-P0399

Pilocarpine Nitrate

Controlled Product

CAS: 148-72-1

Applications Pilocarpine Nitrate is an antiglaucoma agent; miotic; sialogogue.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Shahar, O. et al.: Nucl. Acids Res., 42, 5689 (2014); Li, J. et al.: Int. J. Pharm., 455, 75 (2013);

Formula: C₁₁H₁₆N₂O₂·HNO₃

Color and Shape: Neat

Molecular weight: 271.27

Ref: TR-P441505

Pilocarpine nitrate

CAS: 148-72-1

Pilocarpine nitrate is a cholinergic alkaloid, which is a natural product extracted from the leaves of the Pilocarpus plant, primarily Pilocarpus jaborandi. It functions as a muscarinic receptor agonist, primarily targeting the M3 receptors. This action stimulates the parasympathetic nervous system, leading to an increase in glandular secretions, including saliva and sweat, and contractions of the smooth muscles, particularly in the eye.

Formula: C₁₁H₁₆N₂O₂

Purity: Min. 95%

Molecular weight: 208.26 g/mol

Ref: 3D-FP05595