CAS 148031-34-9: Eptifibatide

Description: Eptifibatide is a synthetic cyclic heptapeptide that functions as a potent inhibitor of platelet aggregation. It is primarily used in clinical settings to prevent thrombotic events in patients undergoing percutaneous coronary interventions or those with acute coronary syndromes. Eptifibatide works by selectively binding to the glycoprotein IIb/IIIa receptor on platelets, thereby blocking the binding of fibrinogen and other adhesive molecules, which is crucial for platelet aggregation. This action helps to reduce the risk of blood clots. The substance is administered intravenously and has a relatively short half-life, necessitating careful monitoring and dosage adjustments. Eptifibatide is generally well-tolerated, but potential side effects may include bleeding complications, thrombocytopenia, and allergic reactions. Its efficacy and safety profile make it a valuable therapeutic agent in cardiology, particularly in acute care settings. As with any medication, its use should be guided by clinical protocols and individual patient considerations.

Formula: C₃₅H₄₉N₁₁O₉S₂

InChI: InChI=1/C35H49N11O9S2/c36-31(52)26-17-57-56-12-10-27(47)43-22(7-3-4-11-39-35(37)38)32(53)41-16-28(48)44-25(14-29(49)50)34(55)45-24(13-18-15-40-20-6-2-1-5-19(18)20)30(51)21-8-9-23(42-21)33(54)46-26/h1-2,5-6,15,21-26,40,42H,3-4,7-14,16-17H2,(H2,36,52)(H,41,53)(H,43,47)(H,44,48)(H,45,55)(H,46,54)(H,49,50)(H4,37,38,39)/t21?,22-,23-,24-,25-,26-/m0/s1

Synonyms:

• [3-carbamoyl-11-{4-[(diaminomethylidene)amino]butyl}-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxodocosahydro-7H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosin-17-yl]acetic acid
• [(1S,4R,12S,18S,21S)-12-(4-carbamimidamidobutyl)-4-carbamoyl-21-(1H-indol-3-ylmethyl)-2,10,13,16,19,22-hexaoxo-6,7-dithia-3,11,14,17,20,26-hexaazabicyclo[21.2.1]hexacos-18-yl]acetic acid
• Map-Lys-Gly-Asp-Trp-Pro-Cys-Nh2
• Integrelin
• N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide
• [(3R,11S,17S,20S,25aS)-11-(4-carbamimidamidobutyl)-3-carbamoyl-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxodocosahydro-7H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosin-17-yl]acetic acid
• Eptifibatide Acetate

L-Cysteinamide,N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1?6)-disulfide

CAS: 148031-34-9

• Formula: C₃₅H₄₉N₁₁O₉S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 831.9619

Eptifibatide

CAS: 148031-34-9

Eptifibatide is an antiplatelet, a cyclic heptapeptide made of 6 amino acids and a mercaptopropionyl.

• Formula: C₃₅H₄₉N₁₁O₉S₂
• Purity: 98%
• Color and Shape: White Powder
• Molecular weight: 831.96

Eptifibatide acetate

CAS: 148031-34-9

Eptifibatide acetate is a heparin-like glycosaminoglycan that prevents coagulation by inhibiting the activation of factor …

• Formula: C₃₅H₄₉N₁₁O₉S₂
• Purity: Min. 95%
• Molecular weight: 832 g/mol