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CAS 148077-13-8

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lincophenicol

Description:
Lincosamide, specifically lincophenicol, is an antibiotic that belongs to the lincosamide class of antibiotics, which are primarily used to treat bacterial infections. It is characterized by its ability to inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the growth and reproduction of susceptible bacteria. Lincophenicol exhibits a broad spectrum of activity against both Gram-positive and some Gram-negative bacteria, making it effective in treating various infections. The compound is typically administered via injection or orally, depending on the formulation and the specific clinical scenario. Its pharmacokinetics include good tissue penetration, which allows it to reach therapeutic concentrations in various body fluids and tissues. However, like many antibiotics, lincophenicol can lead to side effects, including gastrointestinal disturbances and potential allergic reactions. Due to concerns about resistance and toxicity, its use is often reserved for specific cases where other antibiotics may not be effective or appropriate. Overall, lincophenicol is a valuable tool in the antibiotic arsenal, particularly in treating resistant bacterial infections.
Formula:C18H27N3O5
InChI:InChI=1/C18H27N3O5/c1-3-4-12-9-16(20(2)10-12)18(24)19-15(11-22)17(23)13-5-7-14(8-6-13)21(25)26/h5-8,12,15-17,22-23H,3-4,9-11H2,1-2H3,(H,19,24)/t12-,15+,16+,17?/m0/s1
Synonyms:
  • (4S)-N-[(2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]-1-methyl-4-propyl-D-prolinamide
  • 2-Pyrrolidinecarboxamide, N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-1-methyl-4-propyl-, (2S-(2alpha(1S*,2S*),4beta))-
  • Lincophenicol
  • 2-Pyrrolidinecarboxamide, N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-1-methyl-4-propyl-, [2S-[2α(1S*,2S*),4β]]- (9CI)
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Found 1 products.
  • Lincophenicol

    CAS:
    <p>Lincophenicol is an Escherichia coli ribosomal peptidyltransferase-catalyzed puromycin reaction inhibitor.</p>
    Formula:C18H27N3O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:365.42