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CAS 148083-64-1

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Fmoc-Lys(Dnp)-OH

Description:
Fmoc-Lys(Dnp)-OH, also known as Fmoc-Lysine(Dnp)-OH, is a protected amino acid derivative commonly used in peptide synthesis. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino group of lysine, allowing for selective reactions during peptide assembly. The "Dnp" (dinitrophenyl) moiety is typically used for labeling or as a chromophore, facilitating detection and purification processes. This compound is characterized by its stability under basic conditions and its ability to undergo deprotection under mild acidic conditions, making it suitable for solid-phase peptide synthesis. The presence of the lysine side chain provides a reactive amine that can participate in further coupling reactions, enhancing the versatility of this compound in constructing complex peptides. Additionally, Fmoc-Lys(Dnp)-OH is often utilized in research and pharmaceutical applications, particularly in the development of peptide-based drugs and in studies involving protein interactions. Its unique structural features and functional groups make it an essential building block in the field of peptide chemistry.
Formula:C27H26N4O8
InChI:InChI=1/C27H26N4O8/c32-26(33)24(11-5-6-14-28-23-13-12-17(30(35)36)15-25(23)31(37)38)29-27(34)39-16-22-20-9-3-1-7-18(20)19-8-2-4-10-21(19)22/h1-4,7-10,12-13,15,22,24,28H,5-6,11,14,16H2,(H,29,34)(H,32,33)/t24-/m0/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=N[C@@H](CCCCNc1ccc(cc1N(=O)=O)N(=O)=O)C(=O)O)O
Synonyms:
  • (2S)-6-[(2,4-dinitrophenyl)amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
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