CAS 148084-37-1

exfoliamycin

Description:

Exfoliamycin is a chemical compound classified as an antibiotic, specifically belonging to the class of glycopeptides. It is known for its antibacterial properties, particularly against Gram-positive bacteria. The compound is produced by certain strains of the bacterium *Micromonospora* and exhibits a unique mechanism of action by inhibiting cell wall synthesis, which is crucial for bacterial growth and survival. Exfoliamycin has garnered interest in pharmaceutical research due to its potential therapeutic applications, especially in treating infections caused by resistant bacterial strains. Its structure features a complex arrangement of sugar moieties and aromatic rings, contributing to its biological activity. Additionally, exfoliamycin has been studied for its potential use in combination therapies to enhance the efficacy of existing antibiotics. As with many antibiotics, the development of resistance is a concern, prompting ongoing research into its pharmacodynamics and pharmacokinetics to optimize its clinical use.

Formula: C₂₂H₂₆O₉

InChI: InChI=1/C22H26O9/c1-3-4-13-15-9(7-22(2,29)31-13)5-10-12(24)6-11(17(25)16(10)19(15)27)21-20(28)18(26)14(8-23)30-21/h5-6,13-14,18,20-21,23,26-29H,3-4,7-8H2,1-2H3

Synonyms:

• Exfoliamycin
• 1H-Naphtho(2,3-c)pyran-6,9-dione, 3,4-dihydro-3,10-dihydroxy-3-methyl-8-pentofuranosyl-1-propyl-
• 1,4-anhydro-1-(3,10-dihydroxy-3-methyl-6,9-dioxo-1-propyl-3,4,6,9-tetrahydro-1H-benzo[g]isochromen-8-yl)pentitol
• exfoliamycin
• 1H-Naphtho[2,3-c]pyran-6,9-dione, 3,4-dihydro-3,10-dihydroxy-3-methyl-1-propyl-8-β-D-ribofuranosyl-, (1R,3S)-

Exfoliamycin

CAS: 148084-37-1

Exfoliamycin is a naphthoquinone antibiotic found in the Streptomyces strain Exfoliamycin Tu 1424, and it exhibits activity against Gram-positive bacteria.

Formula: C₂₂H₂₆O₉

Color and Shape: Solid

Molecular weight: 434.436

Ref: TM-TN9896