CAS 148182-34-7

tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH

Description:

Tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH, commonly referred to as Boc-Phe-Leu-Phe-Leu-Phe-OH, is a synthetic peptide characterized by its specific amino acid sequence and the presence of a tert-butyloxycarbonyl (Boc) protecting group. This compound is notable for its role in peptide synthesis, particularly in the context of solid-phase peptide synthesis (SPPS), where the Boc group serves to protect the amino group of the phenylalanine residue during the coupling process. The peptide features a sequence that includes multiple phenylalanine and leucine residues, contributing to its hydrophobic nature and potential biological activity. Its structure allows for various applications in research, particularly in studies related to protein interactions and drug design. The compound is typically soluble in organic solvents and may exhibit specific conformational properties influenced by its amino acid composition. As with many peptides, stability and reactivity can be affected by environmental factors such as pH and temperature.

Formula: C₄₄H₅₉N₅O₈

InChI: InChI=1/C44H59N5O8/c1-28(2)23-33(46-41(53)36(26-31-19-13-9-14-20-31)49-43(56)57-44(5,6)7)38(50)47-35(25-30-17-11-8-12-18-30)40(52)45-34(24-29(3)4)39(51)48-37(42(54)55)27-32-21-15-10-16-22-32/h8-22,28-29,33-37H,23-27H2,1-7H3,(H,45,52)(H,46,53)(H,47,50)(H,48,51)(H,49,56)(H,54,55)/t33-,34-,35-,36-,37-/m0/s1

SMILES: CC(C)C[C@@H](C(=N[C@@H](Cc1ccccc1)C(=N[C@@H](CC(C)C)C(=N[C@@H](Cc1ccccc1)C(=O)O)O)O)O)N=C([C@H](Cc1ccccc1)N=C(O)OC(C)(C)C)O

Synonyms:

• Boc-flflf
• Boc-phe(D)-leu-phe(D)-leu-phe-OH
• L-Phenylalanine, N-(N-(N-(N-(N-((1,1-dimethylethoxy)carbonyl)-D-phenylalanyl)-L-leucyl)-D-phenylalanyl)-L-leucyl)-
• N-(tert-butoxycarbonyl)-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-leucyl-L-phenylalanine
• tert-Butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH
• L-Phenylalanine, N-[N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-D-phenylalanyl]-L-leucyl]-D-phenylalanyl]-L-leucyl]- (9CI)

N-Boc-Phe-Leu-Phe-Leu-Phe

CAS: 148182-34-7

N-Boc-Phe-Leu-Phe-Leu-Phe

Purity: ≥98%

Molecular weight: 785.97g/mol

Ref: 54-BUP05093

N-Boc-Phe-Leu-Phe-Leu-Phe

CAS: 148182-34-7

Boc-FLFLF is an FPR1 antagonist that enhances pain and blocks annexin's antinociception, used in FPR studies.

Formula: C₄₄H₅₉N₅O₈

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 785.97

Ref: TM-TP1212