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CAS 148229-79-2

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(-)-TRAMADOL, HYDROCHLORIDE

Description:
(-)-Tramadol hydrochloride is a synthetic opioid analgesic primarily used for the management of moderate to moderately severe pain. It acts on the central nervous system by binding to mu-opioid receptors and inhibiting the reuptake of norepinephrine and serotonin, which contributes to its analgesic effects. The substance is a white to off-white crystalline powder, soluble in water, and has a molecular formula that reflects its complex structure. It is classified as a Schedule IV controlled substance in many jurisdictions due to its potential for abuse and dependence. The pharmacokinetics of (-)-tramadol involve oral bioavailability, with metabolism primarily occurring in the liver, leading to active metabolites. Common side effects include nausea, dizziness, and constipation, while more severe risks involve respiratory depression and seizures, particularly at higher doses or in combination with other central nervous system depressants. Due to its dual mechanism of action, (-)-tramadol is often favored for pain management in patients who may not respond well to traditional opioids.
Formula:C16H26ClNO2
Synonyms:
  • (-)-2-[(Dimethylamino)Methyl]-1-(3-Methoxyphenyl)Cyclohexanol, Hydrochloride
  • (-)-(1S,2S)-Tramadol Hcl
  • (-)-(1S,2S)-Tramadol hydrochloride
  • (1S,2S)-(-)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol Hydrochloride
  • E 381
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