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CAS 148396-36-5

:

Fradafiban

Description:
Fradafiban, with the CAS number 148396-36-5, is a synthetic compound that belongs to the class of small molecule inhibitors. It is primarily recognized for its role as a glycoprotein IIb/IIIa receptor antagonist, which is significant in the context of cardiovascular medicine, particularly in the prevention of thrombus formation. The compound exhibits properties that allow it to inhibit platelet aggregation, making it a candidate for use in various thrombotic disorders. Fradafiban is characterized by its specific binding affinity to the glycoprotein receptors on platelets, which is crucial for its mechanism of action. Additionally, it is typically administered in a clinical setting, often in conjunction with other antiplatelet therapies, to enhance therapeutic efficacy. The pharmacokinetics of Fradafiban, including its absorption, distribution, metabolism, and excretion, are essential for determining its clinical applications and dosing regimens. Overall, Fradafiban represents a significant advancement in antithrombotic therapy, contributing to improved patient outcomes in cardiovascular interventions.
Formula:C20H21N3O4
InChI:InChI=1S/C20H21N3O4/c21-19(22)14-3-1-12(2-4-14)13-5-7-17(8-6-13)27-11-16-9-15(10-18(24)25)20(26)23-16/h1-8,15-16H,9-11H2,(H3,21,22)(H,23,26)(H,24,25)/t15-,16-/m0/s1
InChI key:InChIKey=IKZACQMAVUIGPY-HOTGVXAUSA-N
SMILES:O(C[C@@H]1C[C@@H](CC(O)=O)C(=O)N1)C2=CC=C(C=C2)C3=CC=C(C(=N)N)C=C3
Synonyms:
  • (3S,5S)-5-(((4'-Amidino-4-biphenylyl)oxy)methyl)-2-oxo-3-pyrrolidineacetic acid
  • (3S,5S)-5-[[[4′-(Aminoiminomethyl)[1,1′-biphenyl]-4-yl]oxy]methyl]-2-oxo-3-pyrrolidineacetic acid
  • 3-Pyrrolidineacetic acid, 5-[[[4′-(aminoiminomethyl)[1,1′-biphenyl]-4-yl]oxy]methyl]-2-oxo-, (3S,5S)-
  • 3-Pyrrolidineacetic acid, 5-[[[4′-(aminoiminomethyl)[1,1′-biphenyl]-4-yl]oxy]methyl]-2-oxo-, (3S-trans)-
  • Bibu 52
  • Fradafiban [INN]
  • Unii-Dq0H2B8Ykn
  • [(3S,5S)-5-{[(4'-carbamimidoylbiphenyl-4-yl)oxy]methyl}-2-oxopyrrolidin-3-yl]acetic acid
  • Fradafiban
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Found 1 products.
  • Fradafiban
    Targetmol
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    Fradafiban

    CAS:
    <p>Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.</p>
    Formula:C20H21N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:367.40

    Ref: TM-T11322