CAS 148408-65-5

2,5-Pyrrolidinedione, 1-[[(7S,9aS)-octahydro-2-(2-pyrimidinyl)-2H-pyrido[1,2-a]pyrazin-7-yl]methyl]-, hydrochloride (1:1)

Description:

2,5-Pyrrolidinedione, 1-[[(7S,9aS)-octahydro-2-(2-pyrimidinyl)-2H-pyrido[1,2-a]pyrazin-7-yl]methyl]-, hydrochloride (1:1), with CAS number 148408-65-5, is a chemical compound characterized by its complex structure, which includes a pyrrolidine ring and a bicyclic system featuring a pyrido[1,2-a]pyrazine moiety. This compound is typically encountered as a hydrochloride salt, enhancing its solubility in aqueous environments. The presence of the pyrimidine group suggests potential biological activity, possibly influencing interactions with biological targets. The stereochemistry indicated by the (7S,9aS) notation suggests specific spatial arrangements that may be crucial for its pharmacological properties. As a hydrochloride, it is likely to exhibit improved stability and bioavailability compared to its free base form. The compound's unique structural features may contribute to its potential applications in medicinal chemistry, particularly in the development of therapeutic agents. However, detailed studies would be necessary to elucidate its specific properties, mechanisms of action, and potential uses in various fields.

Formula: C₁₇H₂₃N₅O₂·ClH

InChI: InChI=1S/C17H23N5O2.ClH/c23-15-4-5-16(24)22(15)11-13-2-3-14-12-21(9-8-20(14)10-13)17-18-6-1-7-19-17;/h1,6-7,13-14H,2-5,8-12H2;1H/t13-,14-;/m0./s1

InChI key: InChIKey=HWGPYTRJVVMHGT-IODNYQNNSA-N

SMILES: C([C@@H]1CN2[C@](CN(CC2)C=3N=CC=CN3)(CC1)[H])N4C(=O)CCC4=O.Cl

Synonyms:

• 2,5-Pyrrolidinedione, 1-[[(7S,9aS)-octahydro-2-(2-pyrimidinyl)-2H-pyrido[1,2-a]pyrazin-7-yl]methyl]-, hydrochloride (1:1)
• CP 93393-1
• 2,5-Pyrrolidinedione, 1-[[(7S,9aS)-octahydro-2-(2-pyrimidinyl)-2H-pyrido[1,2-a]pyrazin-7-yl]methyl]-, monohydrochloride
• 2,5-Pyrrolidinedione, 1-[[octahydro-2-(2-pyrimidinyl)-2H-pyrido[1,2-a]pyrazin-7-yl]methyl]-, monohydrochloride, (7S-trans)-
• 2H-Pyrido[1,2-a]pyrazine, 2,5-pyrrolidinedione deriv.

Sunepitron hydrochloride

CAS: 148408-65-5

Sunepitron hydrochloride is a research chemical that has shown potential as an anti-emetic agent. It acts by blocking the neurokinin-1 receptor, which plays a role in the emetogenic response to chemotherapy. Sunepitron hydrochloride has been studied for its ability to reduce nausea and vomiting caused by emetogenic chemotherapy. It has also been investigated for its potential use in combination with other anti-emetic drugs such as palonosetron and arterolane maleate. Additionally, Sunepitron hydrochloride has demonstrated herbicidal activity against triclosan-resistant bacteria and has shown inhibitory effects on thymidylate synthase, an enzyme involved in DNA synthesis.

Formula: C₁₇H₂₃N₅O₂·HCl

Purity: Min. 95%

Molecular weight: 365.86 g/mol

Ref: 3D-YFA40865

Sunepitron HCl

CAS: 148408-65-5

Sunepitron is a combined α2-adrenergic receptor antagonist and 5-HT1A receptor agonist.

Formula: C₁₇H₂₄ClN₅O₂

Color and Shape: Solid

Molecular weight: 365.86

Ref: TM-T28885