CAS 148437-94-9

1H-Imidazo[2,1-b]purine, 1-[2-deoxy-3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl]-4-(phenylmethoxy)-

Description:

1H-Imidazo[2,1-b]purine, 1-[2-deoxy-3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-β-D-erythro-pentofuranosyl]-4-(phenylmethoxy)- is a complex organic compound characterized by its unique structural features, which include an imidazo[2,1-b]purine core and a modified sugar moiety. The presence of the tetrakis(1-methylethyl)-1,3-disiloxanediyl group suggests significant steric hindrance, which may influence its reactivity and solubility. This compound is likely to exhibit biological activity due to its purine structure, which is commonly found in nucleotides and nucleic acids. The phenylmethoxy substituent may enhance lipophilicity, potentially affecting its interaction with biological membranes. Additionally, the presence of the deoxy sugar indicates that it may be involved in nucleoside analog studies or therapeutic applications. Overall, the compound's intricate structure suggests potential utility in medicinal chemistry, particularly in the development of antiviral or anticancer agents. Further studies would be necessary to elucidate its specific properties and biological activities.

Formula: C₃₁H₄₅N₅O₅Si₂

InChI: InChI=1S/C31H45N5O5Si2/c1-20(2)42(21(3)4)38-18-26-25(40-43(41-42,22(5)6)23(7)8)16-27(39-26)36-19-33-28-29(37-17-24-12-10-9-11-13-24)34-31-32-14-15-35(31)30(28)36/h9-15,19-23,25-27H,16-18H2,1-8H3/t25-,26+,27+/m0/s1

InChI key: InChIKey=BLDLNBNHGVBWLB-OYUWMTPXSA-N

SMILES: O(CC1=CC=CC=C1)C=2C3=C(N(C=N3)[C@H]4C[C@]5([C@](O4)(CO[Si](C(C)C)(C(C)C)O[Si](C(C)C)(C(C)C)O5)[H])[H])N6C(N2)=NC=C6

Synonyms:

• 6H-Furo[3,2-f]-1,3,5,2,4-trioxadisilocin, 1H-imidazo[2,1-b]purine deriv.
• 1H-Imidazo[2,1-b]purine, 1-[2-deoxy-3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-β-D-erythro-pentofuranosyl]-4-(phenylmethoxy)-

O6-Benzyl-N2,3-etheno-2’-deoxy-3’,5’-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine

CAS: 148437-94-9

Ref: 7W-GC4080

O6-Benzyl-N2,3-etheno-2'-deoxy-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine

CAS: 148437-94-9

O6-Benzyl-N2,3-etheno-2'-deoxy-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine is a modified nucleoside with antiviral and anticancer activities. It can be used in DNA synthesis to produce oligonucleotides that have been modified at the 2' position. O6-Benzyl-N2,3-etheno-2'-deoxy-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine is also active against diphosphate reductase. CAS No. 148437-94-9

Formula: C₃₁H₄₅N₅O₅Si₂

Purity: Min. 95%

Molecular weight: 623.89 g/mol

Ref: 3D-NB16630