CAS 148440-81-7
:thioperamide maleate salt
Description:
Thioperamide maleate salt is a chemical compound primarily recognized for its role as a selective antagonist of the histamine H3 receptor. This substance is often utilized in pharmacological research to investigate the modulation of neurotransmitter release and its potential therapeutic applications in conditions such as cognitive disorders and sleep regulation. The maleate salt form enhances its solubility and stability, making it more suitable for various formulations. Thioperamide itself is characterized by its thiophene ring structure, which contributes to its biological activity. The compound exhibits a relatively low toxicity profile, but like many pharmacological agents, it may have side effects that warrant careful consideration in experimental settings. Its mechanism of action involves blocking the inhibitory effects of histamine on neurotransmitter release, thereby potentially increasing the availability of other neurotransmitters in the central nervous system. Overall, thioperamide maleate salt serves as a valuable tool in neuropharmacology, aiding in the understanding of histaminergic signaling pathways.
Formula:C15H24N4SC4H4O4
Synonyms:- MR-12842, N-Cyclohexyl-4-(1H-imidazol-4-yl)-1-piperidinecarbothioamide maleate salt
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 5 products.
Thioperamide maleate salt
CAS:Formula:C19H28N4O4SPurity:95%Color and Shape:SolidMolecular weight:408.5150Thioperamide maleate
CAS:<p>Thioperamide maleate (MR-12842 maleate) is an effective and selective antagonist of H3 receptor (Ki = 4.3 nM) for inhibition of [3H]histamine synthesis (Ki = 31</p>Formula:C19H28N4O4SPurity:98.48%Color and Shape:SolidMolecular weight:408.52Thioperamidemiddotmaleate
CAS:Controlled Product<p>Applications Thioperamidemiddotmaleate is a potent and selective histamine H3 receptor antagonist shown to cross the blood-brain barrier.<br></p>Formula:C15H24N4S•x(C4H4O4)Color and Shape:NeatMolecular weight:292.44 + x(116.07)
