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CAS 148504-34-1

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CALCEIN-AM

Description:
Calcein-AM, with the CAS number 148504-34-1, is a cell-permeable fluorescent dye commonly used in biological and biochemical research. It is a non-fluorescent compound that, upon entering live cells, is hydrolyzed by intracellular esterases to produce the fluorescent calcein, which emits green fluorescence. This property makes Calcein-AM particularly useful for assessing cell viability, proliferation, and apoptosis, as it allows researchers to visualize living cells in real-time. The dye is typically characterized by its high sensitivity and specificity for viable cells, as only live cells can convert the non-fluorescent form into the fluorescent product. Additionally, Calcein-AM is often employed in various applications, including flow cytometry, microscopy, and high-throughput screening. Its solubility in organic solvents and water enhances its versatility in experimental setups. However, it is important to handle Calcein-AM with care, as with any chemical reagent, to ensure safety and accuracy in experimental results.
Formula:C46H46N2O23
InChI:InChI=1/C46H46N2O23/c1-25(49)60-21-64-39(55)17-47(18-40(56)65-22-61-26(2)50)15-32-37(68-29(5)53)13-11-35-43(32)70-44-33(16-48(19-41(57)66-23-62-27(3)51)20-42(58)67-24-63-28(4)52)38(69-30(6)54)14-12-36(44)46(35)34-10-8-7-9-31(34)45(59)71-46/h7-14H,15-24H2,1-6H3
InChI key:InChIKey=BQRGNLJZBFXNCZ-UHFFFAOYSA-N
SMILES:O=C1OC2(C=3C(OC=4C2=CC(CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=C(OC(C)=O)C4)=CC(OC(C)=O)=C(CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C3)C=5C1=CC=CC5
Synonyms:
  • -Cellstain-Calcein-AmSolution
  • 3',6'-Di(O-Acetyl)-2',7'-Bis(N,N-Bis(Carboxymethyl)-Aminomethyl)Fluorescein-Tetraacetoxymethyl Ester
  • Acetoxymethyl 2-[[2-(Acetoxymethoxy)-2-Oxo-Ethyl]-[[3',6'-Diacetoxy-5'-[[Bis[2-(Acetoxymethoxy)-2-Oxo-Ethyl]Amino]Methyl]-3-Oxo-Spiro[Isobenzofuran-1,9'-Xanthene]-4'-Yl]Methyl]Amino]Acetate
  • Acetoxymethyl 2-[[2-(Acetoxymethoxy)-2-Oxo-Ethyl]-[[3',6'-Diacetoxy-7'-[[Bis[2-(Acetoxymethoxy)-2-Oxo-Ethyl]Amino]Methyl]-3-Oxo-Spiro[Isobenzofuran-1,9'-Xanthene]-2'-Yl]Methyl]Amino]Acetate
  • Cal-Am
  • Calcein Am, 4Mm In Anhydrous Dmso
  • Calcein O,O'-Diacetate Tetrakis(Acetoxymethyl)Ester
  • Calcein acetoxymethyl ester
  • Calcein-Acetoxymethyl Ester, Diacetate
  • Calcein-Am Solution, 1 Mmol In Dmso*
  • See more synonyms
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