CAS 148504-34-1: CALCEIN-AM

Description: Calcein-AM, with the CAS number 148504-34-1, is a cell-permeable fluorescent dye commonly used in biological and biochemical research. It is a non-fluorescent compound that, upon entering live cells, is hydrolyzed by intracellular esterases to produce the fluorescent calcein, which emits green fluorescence. This property makes Calcein-AM particularly useful for assessing cell viability, proliferation, and apoptosis, as it allows researchers to visualize living cells in real-time. The dye is typically characterized by its high sensitivity and specificity for viable cells, as only live cells can convert the non-fluorescent form into the fluorescent product. Additionally, Calcein-AM is often employed in various applications, including flow cytometry, microscopy, and high-throughput screening. Its solubility in organic solvents and water enhances its versatility in experimental setups. However, it is important to handle Calcein-AM with care, as with any chemical reagent, to ensure safety and accuracy in experimental results.

Formula: C₄₆H₄₆N₂O₂₃

InChI: InChI=1S/C46H46N2O23/c1-25(49)60-21-64-41(55)17-47(18-42(56)65-22-61-26(2)50)15-31-11-35-39(13-37(31)68-29(5)53)70-40-14-38(69-30(6)54)32(12-36(40)46(35)34-10-8-7-9-33(34)45(59)71-46)16-48(19-43(57)66-23-62-27(3)51)20-44(58)67-24-63-28(4)52/h7-14H,15-24H2,1-6H3

InChI key: InChIKey=BQRGNLJZBFXNCZ-UHFFFAOYSA-N

SMILES: O=C1OC2(C3=CC(=C(OC(=O)C)C=C3OC4=CC(OC(=O)C)=C(C=C42)CN(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)CN(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)C=5C=CC=CC15

Synonyms:

• -Cellstain-Calcein-AmSolution
• 3',6'-Di(O-Acetyl)-2',7'-Bis(N,N-Bis(Carboxymethyl)-Aminomethyl)Fluorescein-Tetraacetoxymethyl Ester
• Acetoxymethyl 2-[[2-(Acetoxymethoxy)-2-Oxo-Ethyl]-[[3',6'-Diacetoxy-5'-[[Bis[2-(Acetoxymethoxy)-2-Oxo-Ethyl]Amino]Methyl]-3-Oxo-Spiro[Isobenzofuran-1,9'-Xanthene]-4'-Yl]Methyl]Amino]Acetate
• Acetoxymethyl 2-[[2-(Acetoxymethoxy)-2-Oxo-Ethyl]-[[3',6'-Diacetoxy-7'-[[Bis[2-(Acetoxymethoxy)-2-Oxo-Ethyl]Amino]Methyl]-3-Oxo-Spiro[Isobenzofuran-1,9'-Xanthene]-2'-Yl]Methyl]Amino]Acetate
• Cal-Am
• Calcein Am, 4Mm In Anhydrous Dmso
• Calcein O,O'-Diacetate Tetrakis(Acetoxymethyl)Ester
• Calcein acetoxymethyl ester
• Calcein-Acetoxymethyl Ester, Diacetate
• Calcein-Am Solution, 1 Mmol In Dmso*
• Glycine, N,N′-[[3′,6′-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthene]-2′,7′-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-, 1,1′-bis[(acetyloxy)methyl] ester
• Glycine, N,N′-[[3′,6′-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthene]-2′,7′-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-, bis[(acetyloxy)methyl] ester
• NSC 689290
• Spiro[isobenzofuran-1(3H),9′-[9H]xanthene], glycine deriv.
• Calcein AM

Glycine, N,N'-[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-, 1,1'-bis[(acetyloxy)methyl] ester

CAS: 148504-34-1

• Formula: C₄₆H₄₆N₂O₂₃
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 994.8570400000011

Calcein-AM

CAS: 148504-34-1

Calcein-AM (Calcein acetoxymethyl ester) is a cell-permeable probe used to assess eukaryotic cell viability or …

• Formula: C₄₆H₄₆N₂O₂₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 994.86

Calcein-AM

CAS: 148504-34-1

• Formula: C₄₆H₄₆N₂O₂₃
• Purity: ≥ 90.0%
• Color and Shape: White to pale yellow solid
• Molecular weight: 994.9

Calcein-AM

CAS: 148504-34-1

Calcein-AM is a versatile compound that has various applications in the field of research. It …

• Formula: C₄₆H₄₆N₂O₂₃
• Purity: Min. 95%
• Molecular weight: 994.86 g/mol