CAS 148504-51-2

Ripisartan

Description:

Ripisartan, with the CAS number 148504-51-2, is an angiotensin II receptor antagonist primarily used in the treatment of hypertension. It belongs to the class of medications known as sartans, which work by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict. This action leads to vasodilation, resulting in lower blood pressure. Ripisartan is characterized by its high selectivity for the angiotensin II type 1 receptor, which contributes to its efficacy and safety profile. The compound is typically administered orally and is known for its favorable pharmacokinetic properties, including good bioavailability and a relatively long half-life, allowing for once-daily dosing. Additionally, Ripisartan has been studied for its potential benefits in protecting renal function and reducing cardiovascular risks in patients with diabetes. As with other medications in its class, common side effects may include dizziness, fatigue, and potential interactions with other antihypertensive agents. Overall, Ripisartan represents a valuable option in the management of high blood pressure.

Formula: C₂₃H₂₂N₈O

InChI: InChI=1S/C23H22N8O/c1-3-6-20-19(22-25-23(32)28-31(22)14(2)24-20)13-15-9-11-16(12-10-15)17-7-4-5-8-18(17)21-26-29-30-27-21/h4-5,7-12H,3,6,13H2,1-2H3,(H,28,32)(H,26,27,29,30)

InChI key: InChIKey=OLJAPHMBAMBVKL-UHFFFAOYSA-N

SMILES: C(C=1C=2N(C(C)=NC1CCC)NC(=O)N2)C3=CC=C(C=C3)C4=C(C=CC=C4)C=5NN=NN5

Synonyms:

• 5-Methyl-7-n-propyl-8-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-(1,2,4)-triazolo(1,5-c)pyrimidin-2(3H)-one
• 5-Methyl-7-propyl-8-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl][1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one
• 5-methyl-7-propyl-8-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}[1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one
• Up 269-6
• Up 2696
• [1,2,4]Triazolo[1,5-c]pyrimidin-2(3H)-one, 5-methyl-7-propyl-8-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-
• [1,2,4]Triazolo[1,5-c]pyrimidin-2(3H)-one, 5-methyl-7-propyl-8-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-
• Ripisartan

Ripisartan

CAS: 148504-51-2

Ripisartan

Purity: ≥98%

Molecular weight: 426.47g/mol

Ref: 54-BUP11614

Ripisartan

CAS: 148504-51-2

Ripisartan (UP-269-6) is a potent and specific angiotensin II receptor antagonist that inhibits angiotensin II-mediated sympathetic tachycardia responses.

Formula: C₂₃H₂₂N₈O

Purity: 98.52%

Color and Shape: Solid

Molecular weight: 426.47

Ref: TM-T28540