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CAS 148541-70-2

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Ethyl 5-fluoropyridine-2-carboxylate

Description:
Ethyl 5-fluoropyridine-2-carboxylate is an organic compound characterized by its pyridine ring, which contains a fluorine substituent at the 5-position and an ethyl ester functional group at the carboxylic acid position. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its purity and form. It is soluble in organic solvents such as ethanol and dichloromethane but has limited solubility in water due to its hydrophobic ethyl group. Ethyl 5-fluoropyridine-2-carboxylate is often utilized in pharmaceutical synthesis and research, particularly in the development of biologically active compounds. Its fluorine atom can enhance the lipophilicity and metabolic stability of derivatives, making it a valuable building block in medicinal chemistry. The compound's reactivity is influenced by the electron-withdrawing nature of the fluorine atom, which can affect nucleophilic attack and other chemical transformations. Safety data should be consulted for handling and storage, as with all chemical substances.
Formula:C8H8FNO2
InChI:InChI=1/C8H8FNO2/c1-2-12-8(11)7-4-3-6(9)5-10-7/h3-5H,2H2,1H3
SMILES:CCOC(=O)c1ccc(cn1)F
Synonyms:
  • 2-Pyridinecarboxylic Acid, 5-Fluoro-, Ethyl Ester
  • Ethyl 5-Fluoro-2-Pyridinecarboxylate
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