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CAS 148553-51-9

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(R)-Pregabalin

Description:
(R)-Pregabalin is a pharmaceutical compound primarily used as an anticonvulsant and analgesic. It is a chiral molecule, with the (R) configuration being the active enantiomer that exhibits therapeutic effects. The substance is a derivative of gamma-aminobutyric acid (GABA) and functions by modulating calcium channel activity, which in turn reduces the release of excitatory neurotransmitters. This mechanism contributes to its efficacy in treating neuropathic pain, epilepsy, and generalized anxiety disorder. (R)-Pregabalin is typically administered in oral form and is known for its relatively high bioavailability. The compound is characterized by its solubility in water and organic solvents, which facilitates its formulation in various pharmaceutical preparations. Its safety profile is generally favorable, although side effects can include dizziness, somnolence, and peripheral edema. As a controlled substance in many jurisdictions, (R)-Pregabalin is subject to regulations to prevent misuse and ensure proper medical use.
Formula:C8H17NO2
InChI:InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m1/s1
InChI key:InChIKey=AYXYPKUFHZROOJ-SSDOTTSWSA-N
SMILES:[C@@H](CC(C)C)(CC(O)=O)CN
Synonyms:
  • (3R)-3-(Aminomethyl)-5-methylhexanoic acid
  • (R)-3-(Aminomethyl)-5-methylhexanoic acid
  • (R)-Pregabalin
  • Hexanoic acid, 3-(aminomethyl)-5-methyl-, (R)-
  • Hexanoicacid, 3-(aminomethyl)-5-methyl-, (R)-
  • Pd 144550
  • ent-Pregabalin
  • Hexanoic acid, 3-(aminomethyl)-5-methyl-, (3R)-
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