CAS 148554-65-8: SECO RAPAMYCIN SODIUM SALT
Description:Seco rapamycin sodium salt, with the CAS number 148554-65-8, is a derivative of rapamycin, a macrolide compound originally isolated from the bacterium *Streptomyces hygroscopicus*. This compound exhibits potent immunosuppressive properties, making it valuable in transplant medicine to prevent organ rejection. It functions primarily as an inhibitor of the mammalian target of rapamycin (mTOR), a key regulator of cell growth and proliferation. The sodium salt form enhances its solubility in aqueous solutions, facilitating its use in various pharmaceutical formulations. Seco rapamycin is characterized by its complex molecular structure, which includes a large lactone ring and multiple functional groups that contribute to its biological activity. In addition to its immunosuppressive effects, it has been studied for potential applications in cancer therapy and other conditions related to dysregulated cell growth. Safety and efficacy profiles are critical for its therapeutic use, and ongoing research continues to explore its full potential in clinical settings.
Formula:C51H78NNaO13
InChI:InChI=1/C51H79NO13.Na/c1-31(26-35(5)45(55)47(64-10)46(56)36(6)28-34(4)41(53)23-19-32(2)27-38-21-24-42(54)44(29-38)63-9)16-12-11-13-17-33(3)43(62-8)30-39-22-20-37(7)51(61,65-39)48(57)49(58)52-25-15-14-18-40(52)50(59)60;/h11-13,16-17,19,23,28,31-32,34-35,37-40,42-44,46-47,54,56,61H,14-15,18,20-22,24-27,29-30H2,1-10H3,(H,59,60);/q;+1/p-1/b13-11+,16-12+,23-19-,33-17+,36-28+;/t31-,32+,34-,35-,37-,38+,39+,40+,42-,43+,44-,46-,47+,51-;/m1./s1
