CAS 148564-47-0: Milfasartan

Description: Milfasartan is an angiotensin II receptor antagonist primarily used in the treatment of hypertension. It belongs to the class of medications known as sartans, which function by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby lowering blood pressure. The chemical formula of Milfasartan reflects its complex structure, which includes multiple functional groups that contribute to its pharmacological activity. It is characterized by its high selectivity for the angiotensin II receptor subtype 1 (AT1), which enhances its efficacy in managing blood pressure. Milfasartan is typically administered orally and is known for its favorable pharmacokinetic profile, including good bioavailability and a relatively long half-life, allowing for once-daily dosing. Additionally, it may exhibit beneficial effects on renal function and cardiovascular health. As with other medications in its class, potential side effects can include dizziness, fatigue, and elevated potassium levels, necessitating monitoring during treatment.

Formula: C₃₀H₃₀N₆O₃S

InChI: InChI=1/C30H30N6O3S/c1-4-5-10-26-25(29(37)36(19(2)31-26)18-27-24(15-16-40-27)30(38)39-3)17-20-11-13-21(14-12-20)22-8-6-7-9-23(22)28-32-34-35-33-28/h6-9,11-16H,4-5,10,17-18H2,1-3H3,(H,32,33,34,35)

Synonyms:

• Milfasartan [INN]
• Methyl 2-((4-butyl-2-methyl-6-oxo-5-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-1(6H)-pyrimidinyl)methyl)-3-thiophenecarboxylate
• Unii-8Ual5421Cl
• methyl 2-{[4-butyl-2-methyl-6-oxo-5-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}pyrimidin-1(6H)-yl]methyl}thiophene-3-carboxylate

3-Thiophenecarboxylic acid, 2-[[4-butyl-2-methyl-6-oxo-5-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1(6H)-pyrimidinyl]methyl]-, methyl ester

CAS: 148564-47-0

• Formula: C₃₀H₃₀N₆O₃S
• Molecular weight: 554.6626

Milfasartan

CAS: 148564-47-0

Milfasartan is a drug that belongs to the class of angiotensin II receptor antagonists. It …

• Formula: C₃₀H₃₀N₆O₃S
• Purity: Min. 95%
• Molecular weight: 554.7 g/mol

Milfasartan

CAS: 148564-47-0

Milfasartan: Potent AT1 antagonist, oral, effectively reduces blood pressure in hypertensive rats.

• Formula: C₃₀H₃₀N₆O₃S
• Color and Shape: Solid
• Molecular weight: 554.66