CAS 14860-49-2

Clobutinol

Description:

Clobutinol is a chemical compound primarily recognized for its use as a cough suppressant and expectorant in various medicinal formulations. It belongs to the class of compounds known as butyrophenones and is characterized by its ability to alleviate cough symptoms by acting on the central nervous system. Clobutinol exhibits a moderate lipophilicity, which influences its absorption and distribution in the body. The compound is typically administered in oral form and is known for its relatively low toxicity profile when used as directed. Its mechanism of action involves the suppression of the cough reflex, making it effective in treating dry coughs associated with respiratory conditions. Clobutinol is not widely used in all countries, and its availability may vary due to regulatory considerations. Additionally, it is important to note that while it can provide symptomatic relief, it does not address the underlying causes of cough, and its use should be guided by medical advice.

Formula: C₁₄H₂₂ClNO

InChI: InChI=1S/C14H22ClNO/c1-11(10-16(3)4)14(2,17)9-12-5-7-13(15)8-6-12/h5-8,11,17H,9-10H2,1-4H3

InChI key: InChIKey=KVHHQGIIZCJATJ-UHFFFAOYSA-N

SMILES: C(C(C(CN(C)C)C)(C)O)C1=CC=C(Cl)C=C1

Synonyms:

• 1-(4-Chlorophenyl)-2,3-dimethyl-4-dimethylamino-2-butanol
• 1-(4-Chlorophenyl)-4-(dimethylamino)-2,3-dimethylbutan-2-ol
• 1-p-Chlorophenyl-2,3-dimethyl-4-dimethylamino-2-butanol
• 2-(p-Chlorobenzyl)-3-dimethylaminomethyl-2-butanol
• 4-Chloro-alpha(2-(dimethylamino)-1-methylethyl)alpha-methylbenzeneethanol
• 4-Chloro-α-[2-(dimethylamino)-1-methylethyl]-α-methylbenzeneethanol
• Benzeneethanol, 4-chloro-alpha-(2-(dimethylamino)-1-methyl)-alpha-methyl-
• Benzeneethanol, 4-chloro-alpha-(2-(dimethylamino)-1-methylethyl)-alpha-methyl- (9CI)
• Benzeneethanol, 4-chloro-α-[2-(dimethylamino)-1-methylethyl]-α-methyl-
• Brn 2843490
• Clobutinol [INN]
• Clobutinolum
• Clobutinolum [INN-Latin]
• Phenethyl alcohol, p-chloro-alpha-(2-(dimethylamino)-1-methylethyl)-alpha-methyl-
• Phenethyl alcohol, p-chloro-α-[2-(dimethylamino)-1-methylethyl]-α-methyl-
• Unii-1Ny2Ix043A
• p-Chloro-alpha-(2-(dimethylamino)-1-methylethyl)-alpha-methyl-phenethyl alcohol
• p-Chloro-alpha-(2-(dimethylamino)-1-methylethyl)-alpha-methylphenethyl alcohol
• p-Cloro-alpha-(2-(dimetilamino)-1-metiletil)-alpha-metil fenetil alcool
• p-Cloro-alpha-(2-(dimetilamino)-1-metiletil)-alpha-metil fenetil alcool [Italian]
• Clobutinol
• 4-Chloro-α-[2-(dimethylamino)-1-methylethyl]-α-methylphenethyl alcohol
• 2-(p-Chlorobenzyl)-3-dimethylaminomethyl-2-butano
• 4-Chloro-α-methyl-α-[2-(dimethylamino)-1-methylethyl]phenethyl alcohol
• 1-(p-Chlorophenyl)-4-(dimethylamino)-2,3-dimethyl-2-butanol
• Clobutinol (base and/or unspecified salts)
• Clobutinol USP/EP/BP

Clobutinol

CAS: 14860-49-2

Clobutinol has anti-tussive effects. Clobutinol affects heart rate and blood pressure, it can be used for cough related research [1] [2] [3].

Formula: C₁₄H₂₂ClNO

Color and Shape: Solid

Molecular weight: 255.78

Ref: TM-T60393