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CAS 148608-52-0

:

archaeosine

Description:
Archaeosine is a modified nucleobase found in the transfer RNA (tRNA) of certain archaea, playing a crucial role in the stability and function of tRNA molecules. It is characterized by its unique structure, which includes a purine base that is distinct from the more commonly known nucleobases like adenine, guanine, cytosine, and uracil. Archaeosine is notable for its ability to form stable base pairs, contributing to the proper folding and functionality of tRNA during protein synthesis. Its presence is particularly significant in extremophiles, organisms that thrive in extreme environments, where it may help maintain the integrity of tRNA under harsh conditions. The chemical structure of archaeosine includes a 7-deazaguanine moiety, which is responsible for its unique properties. The CAS number 148608-52-0 specifically identifies this compound, facilitating its recognition in chemical databases and literature. Overall, archaeosine exemplifies the diversity of nucleobases in nature and highlights the evolutionary adaptations of organisms in extreme habitats.
Formula:C12H16N6O5
InChI:InChI=1/C12H16N6O5/c13-8(14)3-1-18(9-5(3)10(22)17-12(15)16-9)11-7(21)6(20)4(2-19)23-11/h1,4,6-7,11,19-21H,2H2,(H3,13,14)(H3,15,16,17,22)/t4-,6-,7-,11-/m1/s1
InChI key:InChIKey=PEMQXWCOMFJRLS-RPKMEZRRSA-N
SMILES:C(=N)(N)C=1C2=C(N(C1)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)NC(N)=NC2=O
Synonyms:
  • 1H-Pyrrolo(2,3-d)pyrimidine-5-carboximidamide, 2-amino-4,7-dihydro-4-oxo-7-beta-D-ribofuranosyl-
  • 1H-Pyrrolo[2,3-d]pyrimidine-5-carboximidamide, 2-amino-4,7-dihydro-4-oxo-7-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
  • 2-Amino-4,7-dihydro-4-oxo-7-beta-D-ribofuranosyl-1H-pyrrolo(2,3-d)pyrimidine-5-carboximidamide
  • 2-Amino-4,7-dihydro-4-oxo-7-β-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide
  • 2-amino-4-oxo-7-(beta-D-ribofuranosyl)-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide
  • 7-Formamido-7-deazaguanosine
  • 2-Amino-4,7-dihydro-4-oxo-7-β-D-ribofuranosyl-1H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide
  • Archaeosine
  • 1H-Pyrrolo[2,3-d]pyrimidine-5-carboximidamide, 2-amino-4,7-dihydro-4-oxo-7-β-D-ribofuranosyl-
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Found 3 products.
  • Archaeosine Acetate Salt
    TRC
    + Info

    Archaeosine Acetate Salt

    Controlled Product
    CAS:
    Formula:C12H16N6O5·C2H4O2
    Color and Shape:Neat
    Molecular weight:384.345

    Ref: TR-A766660

    1mg
    202.00€
    5mg
    874.00€
    10mg
    1,509.00€
  • Archaeosine
    TRC
    + Info

    Archaeosine

    Controlled Product
    CAS:
    Formula:C12H16N6O5
    Color and Shape:Neat
    Molecular weight:324.293

    Ref: TR-A766548

    50mg
    19,421.00€
  • Archaeosine
    Biosynth
    + Info

    Archaeosine

    CAS:
    <p>Archaeosine is a low energy chemical compound that inhibits the enzyme transcriptase polymerase chain reaction (PCR), which is an enzyme that catalyzes the synthesis of DNA from RNA. Archaeosine has significant interactions with human proteins, such as leukocyte antigen, and can be used to study protein-protein interactions and enzyme kinetics. The asymmetric synthesis of archaeosine has been studied in rat liver microsomes, which is a type of cell found in the tissues of the liver. Archaeosine also prevents bacterial enzymes from synthesizing DNA.</p>
    Formula:C12H16N6O5
    Purity:Min. 95%
    Molecular weight:324.29 g/mol

    Ref: 3D-NA159487

    5mg
    15,841.00€