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CAS 148625-77-8

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N-fmoc-L-prolinol

Description:
N-Fmoc-L-prolinol is a chemical compound characterized by its structure, which includes a proline backbone modified with a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is often utilized in peptide synthesis and organic chemistry due to its ability to protect amine functionalities while allowing for selective reactions. N-Fmoc-L-prolinol is a white to off-white solid, and it is soluble in organic solvents such as dichloromethane and dimethylformamide, but it has limited solubility in water. The presence of the Fmoc group provides stability and facilitates the purification of intermediates during synthesis. Additionally, the prolinol moiety contributes to the compound's chirality, making it useful in asymmetric synthesis applications. Its CAS number, 148625-77-8, allows for easy identification in chemical databases. Overall, N-Fmoc-L-prolinol is a valuable reagent in the field of medicinal chemistry and peptide research, enabling the development of various bioactive compounds.
Formula:C20H21NO3
InChI:InChI=1/C20H21NO3/c22-12-14-6-5-11-21(14)20(23)24-13-19-17-9-3-1-7-15(17)16-8-2-4-10-18(16)19/h1-4,7-10,14,19,22H,5-6,11-13H2/t14-/m0/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=O)N1CCC[C@H]1CO
Synonyms:
  • 9H-fluoren-9-ylmethyl (2S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
  • Fmoc-Pro-Ol
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