CAS 148642-42-6

N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1-biphenyl-4-carboxamide hydrate hydrochloride

Description:

N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1-biphenyl-4-carboxamide hydrate hydrochloride, with CAS number 148642-42-6, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple functional groups such as amides, methoxy, and piperazine moieties. This compound is typically classified as a pharmaceutical agent, potentially exhibiting biological activity due to its structural features. It is likely to be soluble in polar solvents, given the presence of the hydrochloride salt form, which enhances solubility and stability in aqueous environments. The oxadiazole ring may contribute to its pharmacological properties, possibly influencing its interaction with biological targets. Additionally, the presence of the biphenyl structure suggests potential for lipophilicity, which can affect its absorption and distribution in biological systems. As with many synthetic compounds, safety and handling precautions are essential, and its use would be governed by regulatory standards in pharmaceutical applications.

Formula: C₂₉H₃₁N₅O₃HCl

Synonyms:

• GR 127935 hydrate hydrochloride

N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1-biphenyl-4-carboxamide hydrate hydrochloride

CAS: 148642-42-6

Formula: C₂₉H₃₂ClN₅O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 534.0491

Ref: IN-DA00ANRI

N-(4-Methoxy-3-(4-methylpiperazin-1-yl)phenyl)-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxamide hydrochloride

CAS: 148642-42-6

N-(4-Methoxy-3-(4-methylpiperazin-1-yl)phenyl)-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxamide hydrochloride

Purity: 98%

Molecular weight: 534.06g/mol

Ref: 54-OR1073891

GR 127935 hydrochloride hydrate

CAS: 148642-42-6

Formula: C₂₉H₃₁N₅O₃·HCl·xH₂O

Molecular weight: 534.05 (anhydrous)

Ref: 7W-GK2898

GR 127935 Hydrochloride Hydrate

Controlled Product

CAS: 148642-42-6

Applications GR 127935 Hydrochloride Hydrate is a 5-HT1B/1D antagonist used in the treatment of depression and anxiety affecting serotonin levels.
References Zhang, H. et al.; Arzneimittei Forschung, 60, 109 (2010);

Formula: C₂₉H₃₁N₅O₃·HCl·x(H₂O)

Color and Shape: Neat

Molecular weight: 497.59+36.46+x(18.02)

Ref: TR-G779520

GR 127935 hydrochloride hydrate

CAS: 148642-42-6

GR 127935 is a 5-hydroxytryptamine (5-HT) receptor antagonist that binds to the 5-HT1A, 5-HT2A, and 5-HT7 receptors. It has been shown to inhibit the proliferation of cancer cells in vitro with a biphasic response, where concentrations of 10 μM or less have an inhibitory effect on cell growth and concentrations above 10 μM have stimulatory effects. The anti-cancer properties of GR 127935 are due to its ability to inhibit the growth of cancer cells by binding to the 5-HT2A receptor, which inhibits the production of TNFα and IL-6 cytokines. GR 127935 also has an inhibitory effect on the release of dopamine by binding to the 5-HT1A receptor. This drug has been shown to be effective against hepatitis C virus (HCV) infection in vivo in animal models. GR 127935 is a potent inhibitor for both 5-

Purity: Min. 95%

Ref: 3D-BG177433

GR 127935 hydrochloride

CAS: 148642-42-6

5-HT1B/1D receptor antagonist

Formula: C₂₉H₃₂ClN₅O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 534.05

Ref: TM-T22806