CAS 148819-94-7

CARBOXY-PTIO

Description:

Carboxy-PTIO, with the CAS number 148819-94-7, is a chemical compound that belongs to the class of nitroxides, which are stable free radicals. This substance is characterized by its ability to act as a nitric oxide scavenger, making it useful in various biochemical and pharmacological applications. Carboxy-PTIO is often employed in research to study the role of nitric oxide in biological systems, particularly in the context of oxidative stress and signaling pathways. The compound typically exhibits good solubility in polar solvents, which facilitates its use in biological assays. Additionally, its stability as a free radical allows it to be utilized in various experimental setups without rapid degradation. The presence of a carboxylic acid functional group in its structure contributes to its reactivity and interaction with other biomolecules. Overall, Carboxy-PTIO serves as a valuable tool in the investigation of nitric oxide's physiological effects and its implications in various diseases.

Formula: C₁₄H₁₆KN₂O₄

InChI: InChI=1/C14H17N2O4.K/c1-13(2)14(3,4)16(20)11(15(13)19)9-5-7-10(8-6-9)12(17)18;/h5-8H,1-4H3,(H,17,18);/q;+1/p-1

SMILES: CC1(C)C(C)(C)N(C(=N1=O)c1ccc(cc1)C(=O)O)O.K

Synonyms:

• Carboxy-Ptio Potassium
• Carboxy-Ptio, Potassium Salt
• 2-(4-Carboxyphenyl)-4,4,5,5-Tetramethyl-Imidazoline-1-Oxyl-3-Oxide Potassium
• 2-(4-Carboxyphenyl)-4,4,5,5-Tetramethylimidazoline-1-Oxyl-3-Oxide, Potassium Salt
• 2-(4-Carboxyphenyl)-4,5-Dihydro-4,4,5,5-Tetramethyl-1H-Imidazol-1-Yloxy-3-Oxide Potassium
• 2-(4-Carboxyphenyl)-4,5-Dihydro-4,4,5,5-Tetramethyl-1H-Imidazolyl-1-Oxy-3-Oxide, Potassium Salt
• 2-(4-Carboxyphenyl)-4,5-Dihydro-4,4,5,5-Tetramethylimidazoline-3-Oxide-1-Oxyl, Potassium Salt
• 4-(1-hydroxy-4,4,5,5-tetramethyl-3-oxido-4,5-dihydro-1H-imidazol-2-yl)benzoate
• potassium [2-(4-carboxylatophenyl)-4,4,5,5-tetramethyl-3-oxido-4,5-dihydro-1H-imidazol-1-yl]oxidanyl

Carboxy-PTIO potassium salt, 98+%

CAS: 148819-94-7

Stable, water-soluble free radical that reacts with nitric oxide (NO) to inhibit NO synthase

Formula: C₁₄H₁₆KN₂O₄

Purity: 98+%

Molecular weight: 315.38

Ref: 02-J61316

1H-Imidazol-1-yloxy,2-(4-carboxyphenyl)-4,5-dihydro-4,4,5,5-tetramethyl-, 3-oxide, potassium salt(1:1)

CAS: 148819-94-7

Formula: C₁₄H₁₈KN₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 317.4020

Ref: IN-DA001L7S

Carboxy-PTIO potassium salt

CAS: 148819-94-7

Formula: C₁₄H₁₆KN₂O₄

Molecular weight: 315.38

Ref: 7W-GK5305

Carboxy-ptio, potassium salt

CAS: 148819-94-7

Carboxy-ptio, potassium salt

Purity: 98%

Molecular weight: 315.39g/mol

Ref: 54-OR8125T

Carboxy-PTIO potassium

CAS: 148819-94-7

Carboxy-PTIO potassium (cPTIO potassium) is a NO scavenger in endothelial cells, inhibiting the accumulation of pterin.

Formula: C₁₄H₁₆KN₂O₄

Purity: 98.14%

Color and Shape: Odorless Blue Powder

Molecular weight: 315.39

Ref: TM-T22623

Carboxy-PTIO Potassium Salt

Controlled Product

CAS: 148819-94-7

Applications Carboxy-PTIO Potassium Salt is a water soluble, stable organic free radical that reacts stoichiometrically with NO. Carboxy-PTIO converts NO to NO2 and does not dramatically affect other NO related metabolites. This scavenger allows for the specific investigation of the effect of NO.
References Akaike, T., et al.: Biochem., 32, 827 (1993); Amano, F., et al.: FEBS Letters, 368, 425 (1995); Yoshida, M., et al.: Biochem. Biophys. Res. Commun., 202, 923 (1994), Huang, J., et al.: JACS, 124, 3473 (2002)

Formula: C₁₄H₁₆N₂O₄·K

Color and Shape: Neat

Molecular weight: 315.39

Ref: TR-C181250