CAS 1488354-15-9

Fulacimstat

CAS: 1488354-15-9

Fulacimstat

Purity: ≥98%

Molecular weight: 487.38g/mol

Ref: 54-BUP04917

Fulacimstat

CAS: 1488354-15-9

Fulacimstat (BAY1142524) (BAY1142524) is a chymase inhibitor, with IC50s of 3, 4 nM for hamster and human chymase enzyme, respectively.

Formula: C₂₃H₁₆F₃N₃O₆

Purity: 99.77%

Color and Shape: Solid

Molecular weight: 487.38

Ref: TM-TQ0035

Fulacimstat

CAS: 1488354-15-9

Fulacimstat is a drug that is used to treat chronic kidney disease and ventricular dysfunction. Fulacimstat blocks angiotensin II, which is a potent vasoconstrictor, by inhibiting the angiotensin-converting enzyme (ACE). It has been shown to have beneficial effects on cardiac function in patients with chronic kidney disease who are undergoing hemodialysis. Fulacimstat has also been shown to reduce blood pressure in patients with renal impairment. Fulacimstat lowers potassium levels and increases serum levels of renin, which may lead to adverse events such as infarction or hyperkalemia. Fulacimstat may be an effective treatment for heart failure, but the safety profile needs to be further investigated before it can be recommended for this use.

Formula: C₂₃H₁₆F₃N₃O₆

Purity: Min. 95%

Molecular weight: 487.4 g/mol

Ref: 3D-NJC35415