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CAS 148893-34-9

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FMOC-ARG(ALOC)2-OH

Description:
FMOC-ARG(ALOC)2-OH, with the CAS number 148893-34-9, is a protected amino acid derivative commonly used in peptide synthesis. The substance features a phenylmethoxycarbonyl (FMOC) group, which serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The presence of two allyloxycarbonyl (ALOC) groups on the arginine side chain provides additional protection for the guanidino group, facilitating the synthesis of complex peptides while preventing unwanted side reactions. This compound is typically utilized in solid-phase peptide synthesis, where the stability of the protecting groups under various reaction conditions is crucial. FMOC-ARG(ALOC)2-OH is characterized by its relatively high stability under basic conditions, while the protecting groups can be selectively removed under specific conditions, allowing for the final deprotection of the peptide. Its solubility in organic solvents and moderate solubility in water makes it versatile for various synthetic applications in biochemistry and medicinal chemistry.
Formula:C29H32N4O8
Synonyms:
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-N',N'-Bis-Allyloxycarbonyl-L-Arginine
  • Fmoc-L-Arg(Alloc)2-Oh
  • Fmoc-N-Omega,N-Omega'-Bis-(Allyloxycarbonyl)-L-Arginine
  • Fmoc-Arg(Alloc)2-OH
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