Amyloid beta (Aβ) peptide, specifically the fragment derived from the amyloid precursor protein (APP), is a significant biomolecule associated with Alzheimer's disease. The peptide is typically formed through the proteolytic cleavage of APP and is known for its role in the formation of amyloid plaques in the brains of Alzheimer's patients. The sequence denoted by "A4" refers to a specific region of the APP that can generate various lengths of Aβ peptides, with Aβ(1-42) being the most studied due to its aggregation propensity and neurotoxicity. The CAS number 148914-08-3 corresponds to a specific variant of this peptide, which may have implications in research related to neurodegenerative diseases. Characteristics of amyloid beta include its hydrophobic nature, propensity to aggregate into oligomers and fibrils, and its ability to disrupt cellular function and promote neuroinflammation. Understanding the properties and behavior of amyloid beta is crucial for developing therapeutic strategies aimed at mitigating its detrimental effects in Alzheimer's disease and related disorders.

AMYLOID BETA/A4 PROTEIN PRECURSOR770 (403-407)

148914-08-3: Amyloid beta (Aβ) peptide, specifically the fragment derived from the amyloid precursor protein (APP), is a significant biomolecule associated with Alzheimer's disease. The peptide is typically formed through the proteolytic cleavage of APP and is known for its role in the formation of amyloid plaques in the brains of Alzheimer's patients. The sequence denoted by "A4" refers to a specific region of the APP that can generate various lengths of Aβ peptides, with Aβ(1-42) being the most studied due to its aggregation propensity and neurotoxicity. The CAS number 148914-08-3 corresponds to a specific variant of this peptide, which may have implications in research related to neurodegenerative diseases. Characteristics of amyloid beta include its hydrophobic nature, propensity to aggregate into oligomers and fibrils, and its ability to disrupt cellular function and promote neuroinflammation. Understanding the properties and behavior of amyloid beta is crucial for developing therapeutic strategies aimed at mitigating its detrimental effects in Alzheimer's disease and related disorders.

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CAS 148914-08-3

AMYLOID BETA/A4 PROTEIN PRECURSOR770 (403-407)

Amyloid β/A4 Protein Precursor770 (403-407) trifluoroacetate salt

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