CAS: 148927-60-0 - L-368,899hydrochloride

Formula: C₂₆H₄₂N₄O₅S₂

InChI: InChI=1S/C26H42N4O5S2/c1-19-7-5-6-8-22(19)29-12-14-30(15-13-29)37(34,35)18-26-11-9-20(25(26,2)3)17-23(26)28-24(31)21(27)10-16-36(4,32)33/h5-8,20-21,23H,9-18,27H2,1-4H3,(H,28,31)/t20-,21+,23+,26-/m1/s1

InChI key: InChIKey=MWIASLNTAGRGGA-ZJPWWDJASA-N

SMILES: O=C(NC1CC2CCC1(CS(=O)(=O)N3CCN(C=4C=CC=CC4C)CC3)C2(C)C)C(N)CCS(=O)(=O)C

Synonyms:

• (2S)-2-Amino-N-[(1S,2S,4R)-7,7-dimethyl-1-[[[4-(2-methylphenyl)-1-piperazinyl]sulfonyl]methyl]bicyclo[2.2.1]hept-2-yl]-4-(methylsulfonyl)butanamide
• (2S)-2-amino-N-[(1S,4R)-7,7-dimethyl-1-({[4-(2-methylphenyl)piperazin-1-yl]sulfonyl}methyl)bicyclo[2.2.1]hept-2-yl]-4-(methylsulfonyl)butanamide
• 1-(((7,7-Dimethyl-2-(2-amino-4-(methylsulfonyl)butyramido)bicyclo(2.2.1)heptan-1-yl)methyl)sulfonyl)-4-(2-methylphenyl)piperazine
• Butanamide, 2-amino-N-(7,7-dimethyl-1-(((4-(2-methylphenyl)-1-piperazinyl)sulfonyl)methyl)bicyclo(2.2.1)hept-2-yl)-4-(methylsulfonyl)-, (1S-(1alpha,2alpha(R*),4beta))-
• Butanamide, 2-amino-N-[(1S,2S,4R)-7,7-dimethyl-1-[[[4-(2-methylphenyl)-1-piperazinyl]sulfonyl]methyl]bicyclo[2.2.1]hept-2-yl]-4-(methylsulfonyl)-, (2S)-
• Butanamide, 2-amino-N-[7,7-dimethyl-1-[[[4-(2-methylphenyl)-1-piperazinyl]sulfonyl]methyl]bicyclo[2.2.1]hept-2-yl]-4-(methylsulfonyl)-, [1S-[1α,2α(R*),4β]]-
• L 368899

L-368899 free base

CAS: 148927-60-0

L-368899: non-peptide, oral oxytocin receptor antagonist (IC50: 8.9 nM), 40x more selective than vasopressin V1a/V2.

• Formula: C₂₆H₄₂N₄O₅S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 554.77

L-368,899 Dihydrochloride

CAS: 148927-60-0

Applications L-368,899 Hydrochloride is an oxytoxin antagonist and may beused in the treatment of early …

• Formula: C₂₆H₄₂N₄O₅S₂· 2(HCl)
• Color and Shape: Off-White
• Molecular weight: 554.77 + 2(36.46)

L 368899

CAS: 148927-60-0

Oxytocin antagonist

• Formula: C₂₆H₄₂N₄O₅S₂
• Purity: Min. 95%
• Molecular weight: 554.77 g/mol