CAS 14899-36-6: Dexamethasone palmitate

Description: Dexamethasone palmitate is a synthetic derivative of dexamethasone, a potent glucocorticoid used primarily for its anti-inflammatory and immunosuppressive properties. This compound is characterized by the esterification of dexamethasone with palmitic acid, which enhances its lipophilicity and alters its pharmacokinetic profile. Dexamethasone palmitate is typically administered via intramuscular or subcutaneous routes, allowing for prolonged release and sustained therapeutic effects. It exhibits anti-inflammatory activity by inhibiting the release of inflammatory mediators and modulating immune responses. The substance is often utilized in various medical applications, including the treatment of conditions such as allergies, autoimmune disorders, and certain types of cancer. Its formulation may include various excipients to improve stability and solubility. As with other corticosteroids, potential side effects may include metabolic changes, increased susceptibility to infections, and adrenal suppression, necessitating careful monitoring during treatment. Overall, dexamethasone palmitate represents a valuable tool in the management of inflammatory and autoimmune conditions.

Formula: C₃₈H₅₉FO₆

InChI: InChI=1S/C38H59FO6/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-34(43)45-26-33(42)38(44)27(2)23-31-30-20-19-28-24-29(40)21-22-35(28,3)37(30,39)32(41)25-36(31,38)4/h21-22,24,27,30-32,41,44H,5-20,23,25-26H2,1-4H3/t27-,30+,31+,32+,35+,36+,37+,38+/m1/s1

InChI key: InChIKey=WDPYZTKOEFDTCU-WDJQFAPHSA-N

SMILES: O=C1C=CC2(C(=C1)CCC3C4CC(C)C(O)(C(=O)COC(=O)CCCCCCCCCCCCCCC)C4(C)CC(O)C32F)C

Synonyms:

• (11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Hexadecanoate
• (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]pregna-1,4-diene-3,20-dione
• DXM-21-palmitate
• Dexamethasone-21-palmitate
• Limethason
• Limethasone
• Lipotalon
• Palmitic acid, 21-ester with 9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]-, (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-palmitate

Dexamethasone palmitate

CAS: 14899-36-6

• Formula: C₃₈H₅₉FO₆
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 630.8699

Dexamethasone palmitate

CAS: 14899-36-6

• Purity: ≥98%
• Molecular weight: 630.87g/mol

Dexamethasone 21-Palmitate-d31

CAS: 14899-36-6

Applications A labelled orticosteroid prodrug for the treatment of eye disorders. References Benameur, H., et …

• Formula: C₃₈D₃₁H₂₈FO₆
• Color and Shape: Neat
• Molecular weight: 662.06

Dexamethasone 21-Palmitate

CAS: 14899-36-6

Applications A corticosteroid prodrug for the treatment of eye disorders. References Benameur, H., et al.: …

• Formula: C₃₈H₅₉FO₆
• Color and Shape: Neat
• Molecular weight: 630.87

Dexamethasone palmitate

CAS: 14899-36-6

DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist …

• Formula: C₃₈H₅₉FO₆
• Purity: 98.08%
• Color and Shape: Solid
• Molecular weight: 630.87

Dexamethasone 21-palmitate

CAS: 14899-36-6

Please enquire for more information about Dexamethasone 21-palmitate including the price, delivery time and more …

• Formula: C₃₈H₅₉FO₆
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 630.87 g/mol