CAS 149-17-7

ftivazide

Description:

Ftivazide, with the CAS number 149-17-7, is a chemical compound that belongs to the class of hydrazine derivatives. It is primarily recognized for its application in the field of pharmaceuticals, particularly as an antihypertensive agent. The compound exhibits properties that allow it to influence vascular resistance and blood pressure regulation. Ftivazide is characterized by its hydrazine functional group, which contributes to its reactivity and biological activity. In terms of physical properties, it is typically a white to off-white crystalline solid, with moderate solubility in water and organic solvents. The compound's mechanism of action involves the inhibition of certain enzymes and pathways that regulate vascular tone. Safety and handling precautions are essential, as with many chemical substances, due to potential toxicity and side effects associated with its use. Overall, ftivazide serves as an important example of how chemical compounds can be utilized in therapeutic applications, particularly in managing cardiovascular conditions.

Formula: C₁₄H₁₃N₃O₃

InChI: InChI=1S/C14H13N3O3/c1-20-13-8-10(2-3-12(13)18)9-16-17-14(19)11-4-6-15-7-5-11/h2-9,18H,1H3,(H,17,19)

InChI key: InChIKey=PSWOBQSIXLVPDV-UHFFFAOYSA-N

SMILES: C(NN=CC1=CC(OC)=C(O)C=C1)(=O)C=2C=CN=CC2

Synonyms:

• 4-Pyridinecarboxylic acid, ((4-hydroxy-3-methoxyphenyl)methylene)hydrazide
• 4-Pyridinecarboxylic acid, ((4-hydroxy-3-methoxyphenyl)methylene)hydrazide (9CI)
• 4-Pyridinecarboxylic acid, 2-[(4-hydroxy-3-methoxyphenyl)methylene]hydrazide
• Brn 0234808
• Ftivazid
• Ftivazida
• Ftivazida [INN-Spanish]
• Ftivazide [INN]
• Ftivazidum
• Ftivazidum [INN-Latin]
• Isonicotinic acid vanillylidenehydrazide
• N'-[(3-methoxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]pyridine-4-carbohydrazide
• N'-[(E)-(3-methoxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]pyridine-4-carbohydrazide
• N'-[(Z)-(3-methoxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]pyridine-4-carbohydrazide
• N-Isonicotinamido-3-methoxy-4-hydroxybenzalimine
• Nsc 31725
• Phthivazid
• Phthivazide
• Phthivazidum
• Phtivazid
• Phtivazide
• Unii-40Q4C3O4V0
• Vancide
• Vanicid
• Vanillaberon
• Vanizide
• Ftivazide
• 4-22-00-00598 (Beilstein Handbook Reference)

Phthivazid

CAS: 149-17-7

Color and Shape: Neat

Ref: 61-FOR3191.00

Phthivazid

CAS: 149-17-7

Formula: C₁₄H₁₃N₃O₃

Color and Shape: Neat

Molecular weight: 271.27

Ref: 86-MM3191.00

Isonicotinic Acid Vanillylidenehydrazide

Controlled Product

CAS: 149-17-7

Applications Isonicotinic Acid Vanillylidenehydrazide exhibits anti-mycobacterial activity against Mycobacterium tuberculosis and anti-microbial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Candida albicans, and Aspergillus niger.Also, it is derived from Isoniazid (I821450), which is an antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic).
References Judge, V., et al.: Med. Chem. Res., 21, 1451-1470 (2012); Brewer, G.A., et al.: Anal. Profiles Drug Subs., 6, 183 (1977), Weber, W.W., et al.: Clin. Pharmacokinet., 4, 401 (1979)

Formula: C₁₄H₁₃N₃O₃

Color and Shape: Neat

Molecular weight: 271.27

Ref: TR-I821765

Phthivazid

CAS: 149-17-7

Phthivazid is an antibiotic, which is a synthetic derivative of isonicotinic acid hydrazide. It functions by inhibiting the synthesis of mycolic acids in the mycobacterium cell wall, which are essential components for the survival of the bacteria. This disruption in the cell wall synthesis results in bactericidal activity against Mycobacterium tuberculosis.

Formula: C₁₄H₁₃N₃O₃

Purity: 90% Min

Color and Shape: Powder

Molecular weight: 271.27 g/mol

Ref: 3D-AAA14917