CAS 149-87-1

DL-Pyroglutamic acid

Description:

DL-Pyroglutamic acid, also known as 5-oxoproline, is a cyclic derivative of the amino acid glutamic acid. It is characterized by its white crystalline appearance and is soluble in water, making it readily available for various biochemical applications. The compound features a five-membered lactam ring, which contributes to its unique properties and reactivity. DL-Pyroglutamic acid plays a significant role in the synthesis of proteins and is involved in various metabolic pathways, particularly in the context of amino acid metabolism. It is often utilized in the pharmaceutical and cosmetic industries due to its potential antioxidant properties and its role as a precursor in the synthesis of other biologically active compounds. Additionally, it has been studied for its neuroprotective effects and its potential role in cognitive function. As with many chemical substances, safety and handling precautions should be observed, as it may cause irritation upon contact with skin or eyes.

Formula: C₅H₇NO₃

InChI: InChI=1/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1

InChI key: InChIKey=ODHCTXKNWHHXJC-UHFFFAOYSA-N

SMILES: C(O)(=O)C1NC(=O)CC1

Synonyms:

• (+/-)-2-Pyrrolidinone-5-Carboxylic Acid
• (+/-)-2-Pyrrolidone-5-Carboxylic Acid
• (±)-Pyroglutamic acid
• 5-Oxo-<span class="text-smallcaps">DL</span>-proline
• 5-Oxo-Dl-Proline
• 5-Oxoproline
• 5-Oxopyrrolidine-2-carboxylic acid
• 5-oxo-L-proline
• <span class="text-smallcaps">DL</span>-2-Pyrrolidinone-5-carboxylic acid
• <span class="text-smallcaps">DL</span>-2-Pyrrolidone-5-carboxylic acid
• <span class="text-smallcaps">DL</span>-Proline, 5-oxo-
• <span class="text-smallcaps">DL</span>-Pyroglutamate
• <span class="text-smallcaps">DL</span>-Pyroglutamic acid
• <span class="text-smallcaps">DL</span>-Pyrrolidonecarboxylic acid
• DL-2-Pyrrolidone-5-Carboxylic Acid
• Dl-5-Oxoproline
• Dl-A-Pyroglutamic Acid
• Dl-Glutamic Acid Lactam
• Dl-Proline, 5-Oxo-
• H-Dl-Pyr-Oh
• NSC 40887
• Proline, 5-oxo-
• Proline, 5-oxo-, <span class="text-smallcaps">DL</span>-
• DL-Pyrrolidonecarboxylic acid
• Proline, 5-oxo-, DL-
• DL-pGlu-OH
• DL-2-PYRROLIDINONE-5-CARBOXYLIC ACID
• Pyroglutamic acid and esters
• D,L-2-PYRROLIDONE-5-CARBOXYLIC ACID
• (n)-2-pyrrolidinone-5-carboxylic acid
• DL-5-OXO-2-PYRROLIDINECARBOXYLIC ACID
• DL-5-PYRROLIDONE-2-CARBOXYLIC ACID
• LABOTEST-BB LT00005913
• 5-OXO-PYRROLIDINE-2-CARBOXYLIC ACID
• DL-Pyroglutamic

DL-Pyroglutamic Acid

CAS: 149-87-1

Formula: C₅H₇NO₃

Purity: >99.0%(T)

Color and Shape: White powder to crystal

Molecular weight: 129.12

Ref: 3B-G0061

(+/-)-2-Pyrrolidinone-5-carboxylic acid, 99%

CAS: 149-87-1

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. Th

Formula: C₅H₇NO₃

Purity: 99%

Color and Shape: Pale cream, Crystals or powder or crystalline powder

Molecular weight: 129.12

Ref: 02-L09424

Proline, 5-oxo-

CAS: 149-87-1

Formula: C₅H₇NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 129.1140

Ref: IN-DA001LC1

DL-Pyroglutamic acid

CAS: 149-87-1

DL-Pyroglutamic acid

Purity: 97%

Molecular weight: 129.11g/mol

Ref: 54-OR350322

DL-Pyroglutamic acid

CAS: 149-87-1

DL-Pyroglutamic acid

Purity: ≥98%

Molecular weight: 129.11g/mol

Ref: 54-BUP18920

2-Pyrrolidone-5-carboxylic acid

CAS: 149-87-1

Formula: C₅H₇NO₃

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 129.12

Ref: 7W-GM6837

Carglumic Acid Impurity 2

CAS: 149-87-1

Formula: C₅H₇NO₃

Molecular weight: 129.12

Ref: 4Z-C-138007

DL-Pyroglutamic acid

CAS: 149-87-1

DL-Pyroglutamic acid exhibited a strong inactivating effect on hepatitis B surface antigen. 

Formula: C₅H₇NO₃

Purity: 99.88%

Color and Shape: White Powder

Molecular weight: 129.11

Ref: TM-T9371

5-Oxopyrrolidine-2-carboxylic acid

CAS: 149-87-1

Formula: C₅H₇NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 129.115

Ref: 10-F214708

DL-2-Pyrrolidone-5-carboxylic Acid

Controlled Product

CAS: 149-87-1

Applications DL-2-Pyrrolidone-5-carboxylic Acid is used in the preparation of AZT steroid conjugates as potent anti-HIV agents.
References You, Z. et al.: Nucleos. Nucleot. Nucl. Acids, 25, 37 (2006);

Formula: C₅H₇NO₃

Color and Shape: Neat

Molecular weight: 129.11

Ref: TR-P997960

DL-Pyroglutamic acid

CAS: 149-87-1

DL-Pyroglutamic acid is an antibiotic that has been shown to inhibit the growth of bacteria by binding to a bacterial pyrophosphate-binding site. It also inhibits the production of cyclase and its activity in mice with bowel disease. DL-Pyroglutamic acid has been shown to be effective against a variety of bacterial types, including Gram-positive and Gram-negative bacteria. The compound binds to ferrous iron (Fe2+) with high affinity and forms stable metal complexes that are insoluble in water. This property makes it a useful tool for chromatographic analysis. DL-Pyroglutamic acid has also been shown to have anti-tumor activity in mouse models, although it is not effective at treating human cancer cells.

Formula: C₅H₇NO₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 129.11 g/mol

Ref: 3D-FP39320